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Father diagnosed with PSA 40 Gleason 10 What is this ?

 
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tomm
New User


Joined: 29 Jan 2008
Posts: 1

PostPosted: Tue Jan 29, 2008 11:29 am    Post subject: Father diagnosed with PSA 40 Gleason 10 Reply with quote

Hi,

Father diagnosed with Prostate Cancer

PSA 40
Gleason 5+5=10
Mets in Bones and Lymph
Age 68

Undergoing HDT with Injection and Casodex, I am shattered by this news and would like to know:

What does it mean in terms of life expectancy ?

What does it mean in terms of Quality of Life?

Tomm
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Replicant
Moderator


Joined: 01 Nov 2006
Posts: 744

PostPosted: Tue Jan 29, 2008 1:00 pm    Post subject: hi Reply with quote

I'm sorry to hear about your father.

I think the answer is--you'll have to wait and see. Some men see a huge response to androgen deprivation therapy and go on to live relatively unaffected by PCa for years. In other cases it's not so successful. MOST men experience some level of success with ADT.

It all depends on how long it takes for your dad's cancer to become hormone refractory.

After that, there are chemo drugs.

Has your dad considered a clinical trial?
_________________
Replicant

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T2c, NXMX, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 (and thereafter) <0.1
http://pcabefore50.blogspot.com
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brainman
Site Admin


Joined: 13 Oct 2005
Posts: 5617
Location: Tennessee

PostPosted: Tue Jan 29, 2008 3:11 pm    Post subject: Re: Father diagnosed with PSA 40 Gleason 10 Reply with quote

Hi tomm. I am very sorry about your father's cancer. Prostate Cancer with a Gleason Score of 10 is as aggressive as Prostate Cancer can get. He really needs to receive the most aggressive treatment possible. If he is not at a research hospital, he should ask for a referral to one.

Your father is in my thoughts and prayers.
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Jim
Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendroglioma grade 3, same location.
http://cancerforums.net/viewtopic.php?t=2405
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johnw100
Senior User


Joined: 15 Apr 2006
Posts: 202
Location: australia

PostPosted: Tue Jan 29, 2008 6:17 pm    Post subject: Re: Father diagnosed with PSA 40 Gleason 10 Reply with quote

As suggested in previous reply, life expectancy can vary a lot, as can quality of life, however we can have a large influence on these aspects ourselves.

Two men I know currently use hormone treatment. Both are doing well, and are not obsessive about their situation.
One is 90 and has remained active, with his life going along as before: he still drives, sometimes an hour trip each way to visit.
I usually go with him every 3 months for his specialist consultations and implants, but apart from that I do not continually discuss Prostate Cancer or treatment unless the subject comes up. Lifestyle, diet and similar subjects are often discussed as they are important.
His pre-treatment PSA was 50 and has now reduced to .04 with few acute side effects.

Side effects can vary a lot from person to person, and are influenced by time, change in medication and lifestyle changes, remaining active, diet, supplements.

The book by Dr Charles Myers, "Beating Prostate Cancer: Hormonal Therapy and Diet" is essential reading for anyone on hormone treatment.

Dr Myers indicates that he was surprised to find that most men who are diagnosed as "hormone resistant" actually aren't which translates into prolonged survival and, or course, quality of life.

The yananow website has stories and personal experiences from men who have used all treatments including hormones, in the mentors experiences section. The will also provide any additional information if requested.
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johnw100
Senior User


Joined: 15 Apr 2006
Posts: 202
Location: australia

PostPosted: Tue Jan 29, 2008 7:22 pm    Post subject: Re: Father diagnosed with PSA 40 Gleason 10 Reply with quote

Regarding clinical trials, I have read that Mayo Clinic is to conduct further trials of MDX010 for people on hormone treatment. Ref # 00170157
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Dorothy123
New User


Joined: 22 Jan 2008
Posts: 6

PostPosted: Wed Mar 19, 2008 4:18 am    Post subject: Re: Father diagnosed with PSA 40 Gleason 10 Reply with quote

Dear Tomm,

Sorry to heard that! Don't too upset about your father's Prostate Cancer. Because nothing is absolute, why not try some natural therapy such as the acupuncture or herbal medicine together with the hormone treatment.
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