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Doctors May Spot Which Lesions Likely to Progress to Prostat What is this ?

 
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interval
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Joined: 11 Apr 2008
Posts: 43

PostPosted: Sun May 04, 2008 4:01 pm    Post subject: Doctors May Spot Which Lesions Likely to Progress to Prostat Reply with quote

A Spanish study has found a way to tell which suspicious prostate lesions are likely to develop into cancer. The conclusions show a link between high-grade prostatic intraepithelial neoplasia (HG-PIN) lesions and the PTOV1 gene. The more PTOV1 the lesion expresses, the more likely cancer will develop. The report also backs the reverse - that the lack of PTOV1 means a reduced risk of prostate cancer.

PTOV1 is a protein that researchers don’t fully understand the function of, but they have previously found too much of it appears to promote the spread of cancer cells.

The findings are published in the May 1 issue of Clinical Cancer Research. They could help men with precancerous lesions avoid unnecessary needle biopsies.
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Replicant
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Joined: 01 Nov 2006
Posts: 744

PostPosted: Mon May 05, 2008 12:10 pm    Post subject: link to a story on PTOV1 Reply with quote

http://www.sciencedaily.com/releases/2008/05/080501062750.htm
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Replicant

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T2c, NXMX, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 (and thereafter) <0.1
http://pcabefore50.blogspot.com
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brainman
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Joined: 13 Oct 2005
Posts: 5617
Location: Tennessee

PostPosted: Mon May 05, 2008 5:42 pm    Post subject: Re: Doctors May Spot Which Lesions Likely to Progress to Prostat Reply with quote

Replicant, it seems like when a member post a piece of news, you always take the time to hunt up the actual article. On behalf of all of us, I would like to thank you for your efforts.
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Jim
Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendroglioma grade 3, same location.
http://cancerforums.net/viewtopic.php?t=2405
My Story Part 1: http://cancerforums.net/viewtopic.php?t=2528
My Story Part 2: http://cancerforums.net/viewtopic.php?p=7350
My Story Part 3: http://cancerforums.net/viewtopic.php?t=8029
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