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Is lung Cancer hereditary? What is this ?

 
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jb
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Joined: 05 Feb 2006
Posts: 18
Location: UK
PostPosted: Thu Mar 30, 2006 8:10 am    Post subject: Is lung Cancer hereditary? Reply with quote
Hi Smile
My dad was dx'd with Nsclc in Feb.
Is it likely that as a family any of us would now be at risk of getting it as well?
I ask because my father and myself both had TB.
My dad had it when he was a teenager and i had it 25 yrs ago when i was about 12.
My dad and the rest of my family (mum,1 brother,1 sister) are smokers but i have never smoked
I go for chest x rays roughly every 5/6 yrs and just wondered if its something i should mention to my doctor if and when i have another xray.
Thanks
Jackie
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Anneli
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Joined: 14 Feb 2006
Posts: 13
Location: Finland
PostPosted: Fri Mar 31, 2006 2:18 pm    Post subject: Re: Is lung Cancer hereditary? Reply with quote
Hi Jackie!Smile

Yes, it's believed to be hereditary. See this article about the lung cancer gene.

http://www.karmanos.org/view_news.asp?id=149

Personally I'm sure that it's hereditary. My paternal grandfather had lung cancer, and now my father has it as well. And my father has never smoked in his whole life.

Anneli
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Anneli
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Joined: 14 Feb 2006
Posts: 13
Location: Finland
PostPosted: Mon Apr 03, 2006 7:10 am    Post subject: Re: Is lung Cancer hereditary? Reply with quote
And also this:

Cancer susceptibility in families
Agencies
Sunday, April 02, 2006 23:45 IST

Studying thousands of people, researchers at The University of Texas Madison, Anderson Cancer Centre have documented a 25 per cent increased risk of developing one of a number of cancers in first-degree relatives of lung cancer patients who have never smoked compared to families of people who neither smoke nor have lung cancer.

Researchers say their study, one of the largest ever done and the only one to include both men and women, strongly suggests that these lung cancer patients and their affected relatives share an inherited genetic susceptibility to cancer development.

Such marked cancer susceptibility also likely explains why patients in this study, who never smoked but might have been exposed to secondhand smoke, developed lung cancer in the first place, says the study author Olga Gorlova.


http://www.dnaindia.com/report.asp?NewsID=1021722
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