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Pepper cured my prostate cancer !! What is this ?
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HaydnLover
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Joined: 09 Mar 2008
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Location: Florida

PostPosted: Sun Mar 09, 2008 8:38 pm    Post subject: Pepper cured my prostate cancer !! Reply with quote

In April 2006 I was diagnosed with prostate cancer after a biopsy - Gleason score 6(3+3). I was strongly urged to have the prostate removed immediately. I refused & starting doing research. I found a Cedars-Sinai Medical Center/UCLA School of Medicine study that said that capsaicin (the stuff that makes pepper hot) fed to rats bred to have human prostate cancer had caused the tumors to die! (I put a link here to the study report but it has been removed by the admin - search for "prostate cancer study" & you will find it)

I immediately started taking cayenne pepper capsules daily. I took the equivalent human dose from the study, doubled that & made that my goal. I gradually consumed more each week until I reached what I thought was the right dose. I had improved symptoms within the first two weeks - urination was easier - I had not been able to reach orgasm at the time of diagnosis but that too improved & is still improving.

Last month I decided to see a urologist to see what was involved in "Watchful Waiting" - he wanted to do another biopsy since it had been two years - I agreed & the results came back clean - they found no cancer - not a trace! My doctor was stunned & said that in 18 years he had never seen such a result. We had it double checked & I am indeed cancer free.

I am confident it was the cayenne that made the tumor disappear - given the study results.

I plan to keep taking it indefinitely & I recommend it to any male who has been diagnosed with either BPH or prostate cancer.


Last edited by HaydnLover on Mon Mar 10, 2008 1:14 pm; edited 1 time in total
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brainman
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Location: Tennessee

PostPosted: Mon Mar 10, 2008 1:17 am    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

Hi HaydnLover, I am glad that your cancer has responded the the capsaicin treatment you have been using. My concern for you is that I know the biopsies of the Prostate have a higher then "normal" number of face negative results. What is your PSA and free PSA? What were they originally... when you where first diagnosed?

I deleted the link you used because you have not yet earned the privilege to you links to outside websites. You have to be a member for at least one month and have posted at least 10 significant messages in order to use lings.

You are in my thoughts and prayers.
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Site Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendoglioma grade 3, same location.
My Story Part 1: http://cancerforums.net/viewtopic.php?p=7350
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HaydnLover
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Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Mon Mar 10, 2008 1:17 pm    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

Brainman,
Sorry about busting the rules - just got the email with the rule this morning after I had already posted.
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Replicant
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Joined: 01 Nov 2006
Posts: 195

PostPosted: Mon Mar 10, 2008 3:13 pm    Post subject: tolerating capsaicin Reply with quote

I'd agree with Brainman that, using Occam's Razor (thinking horses rather than zebras when you hear hoofbeats) that it's more likely your first biopsy was misread or your second biopsy missed the cancer. If your Gleason was originally 3+3, that could mean a pretty tame cancer without many focal points. It would be easy for a second biopsy to miss it. I too am interested in what your PSA has been doing. I would also say it seems possible, given the animal studies, that the pepper reduced the size of the cancerous tissue, and although not cured, it was not found again on biopsy. I'm just speculating here..

I like to keep an open mind and I'm willing to admit I don't know whether or not cayenne could have cured your cancer. There has been a recent flurry of research that is promising. What I saw most recently was that it worked well in culture and in 80% of mice it shrank their tumors to 1/5 of their original size, although it did not cure them. But they were fed the equivalent of a person eating 3-8 habanero peppers (very, very hot) every day and I'm not sure many people could tolerate that level of spice.

Here's the article I was reading. Pretty sure it's the same one you referenced:
http://www.eurekalert.org/pub_releases/2006-03/aafc-pch031306.php

I see that you've posted this on other websites, and as far as I can tell, you're not trying to sell anything or even promote a particular brand or source.

I tried taking a cayenne supplement once and after one pill, I thought I was on fire...which leads me to ask--how do you tolerate the cayenne?

Also--I wonder what was causing your urination problem and how did the pepper help? It almost certainly would not have been caused by prostate cancer, since urinary symptoms don't show up with 3+3 (usually--goruck might have something to say on this). Pepper for BPH? The same goes for sexual performance--I don't see the connection.

A very interesting post...
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Replicant

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T3a, N0M0, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 <0.1, 12/07 <0.1, 4/08 <0.1
http://pcabefore50.blogspot.com
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HaydnLover
Regular


Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Mon Mar 10, 2008 4:03 pm    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

Hi Replicant,

I'm happy to have found the person who knows what "most likely happened". Where were you when I needed you? 8>)

I think it is most likely that the pepper did what it did in the study. Yes, it just reduced the size of the tumors in the study but it did that by causing the cancer cells to commit suicide, hence a smaller tumor. There is every reason to believe that had the study gone on long enough the tumors would be reduced to zero size, i.e. a cure. I've taken high doses of cayenne for two years now.

I don't know what the connection is between cayenne & improved sexual performance or urinary function, I'm just telling you what happened to me. As you said, I'm not selling anything just sharing my experience.

You say confidently that there is no connection - my uroligist says that an inability to climax was related to the cancer, as was the urination problem due to the increased size of the prostate - just like in BPH.

It is obvious to me from this post & some others on other forums that there are some people who take umbrage with my saying I am cured & feel the need to tell me that I'm probably not. Fine, let's call it an apparent cure (as I did on another forum) or a possible cure, I don't care.

I know the tumor was small to begin with - that's what the biopsy said & that's why I refused treatment.

Now, am I "cured"? Only time will tell. The study found that pepper caused cancer cells to self destruct in mice & it seems to have happened in me. The first 6 core biopsy found the tumor & then two years later a 12 core biopsy cannot find any cancer cells - that sounds closer to "cure" than failure to me.

There is a cayenne cap that has added ginger - people that can't take cayenne alone seem to tolerate this better. I have no problem with straight cayenne - the key is gradually adding to the dose. I started taking one 40,000 heat unit cap before each of two meals a day & added another 40,000 cap per dose per week. I now take five 600mg 100,000 heat unit caps twice a day before meals. the body does acclimate to the cayenne & an interesting side effect is I can now eat the hottest Thai or Indian food without discomfort.


Last edited by HaydnLover on Thu Mar 13, 2008 11:33 pm; edited 1 time in total
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goruck
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Joined: 22 May 2006
Posts: 51
Location: sarasota florida

PostPosted: Tue Mar 11, 2008 9:32 pm    Post subject: george rucker urology Reply with quote

Hi,

What was the amount of cancer in each core and what was your original psa?

What is your psa now?

The two experienced board users have made excellent statistical points here.

george rucker, urology/urologist
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George Rucker
Urology/Urologist
http://prostateconcerns.blogspot.com/
www.urology-partners.com
http://www.cornellurology.com/past-res.html
http://www.lakewoodranchmedicalcenter.com/index.php?&PageID=1088
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HaydnLover
Regular


Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Tue Mar 11, 2008 10:15 pm    Post subject: Re: george rucker urology Reply with quote

Hi George,

It is great to have a urologist aboard. After my second biopsy I told my urologist about my the study & my pepper regimen & that I thought the pepper was responsible. He just smiled & said "Sometime miracles do happen" - no further interest expressed!

My PSA had been around 2.2 for years, was not tested for a couple of years & then at the time of diagnosis was 4.8

Between then & now my PSA has varied between 4.5 & 3.6 - I'm going to my primary tomorrow & will get the results of my last PSA test a month ago - I will post the results.

The biopsy said left side of prostate normal - right side: adenocarcinoma - the tumor had Gleason's combined score 6 (3+3) & involved 25-30% of the tissue in two of 6 needle cores. I had the biopsy double checked.

The second biopsy in April 2008 was 12 core & completely free of any signs of cancer. Again, the biopsy was double checked.

I'm curious if you have read this study & any thoughts on my experience you would care to share
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72 years old.
2006 biopsy found cancer Gleason score 6 (3+3)
2008 biopsy - no cancer
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brainman
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Joined: 13 Oct 2005
Posts: 3697
Location: Tennessee

PostPosted: Tue Mar 11, 2008 11:32 pm    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

HaydnLover, 4.8 is a signifacantly high PSA Confused. You should really reconcider more traditional forms of therapy. Even with a PSA of 3.6, there is a significant likelihood that your second biopsy was a false negative.
_________________
Jim
Site Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendoglioma grade 3, same location.
My Story Part 1: http://cancerforums.net/viewtopic.php?p=7350
My Story Part 2: http://cancerforums.net/viewtopic.php?t=8029
Blog http://jimhawkinsport.blogspot.com/
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goruck
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Joined: 22 May 2006
Posts: 51
Location: sarasota florida

PostPosted: Thu Mar 13, 2008 7:46 am    Post subject: george rucker urologist Reply with quote

Haydn,

Thank you for sharing your information with us. I will re read the original article and post my thoughts.

George Rucker
urology/urologist
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Urology/Urologist
http://prostateconcerns.blogspot.com/
www.urology-partners.com
http://www.cornellurology.com/past-res.html
http://www.lakewoodranchmedicalcenter.com/index.php?&PageID=1088
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goruck
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Joined: 22 May 2006
Posts: 51
Location: sarasota florida

PostPosted: Thu Mar 13, 2008 7:49 am    Post subject: questions Reply with quote

Haydn,

What is your weight?
What was the ultimate dose you took?
Where did you obtain your capsules?


feel free to email me at goruck@gmail.com as where you obtained the capsules may not be information allowed on this board due to spamming in the past by unscrupulous individuals.

I am actually contacting my old contacts at sloan kettering and ucla in rote bench research to obtain follow up and current thinking on this topic.

best

george rucker urologist
urology
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Urology/Urologist
http://prostateconcerns.blogspot.com/
www.urology-partners.com
http://www.cornellurology.com/past-res.html
http://www.lakewoodranchmedicalcenter.com/index.php?&PageID=1088
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HaydnLover
Regular


Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Thu Mar 13, 2008 9:05 am    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

Thanks George for following up on this.

Your questions=

I weigh 175lbs

I am now taking ten 600mg capsules of 100,000 heat unit capsules per day - 5 before each of two meals.

I buy the cayenne at a "health food" store in St Petersburg. It is food grade, sold as a supplement, packaged by a national vitamn manufactor.
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72 years old.
2006 biopsy found cancer Gleason score 6 (3+3)
2008 biopsy - no cancer
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goruck
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Joined: 22 May 2006
Posts: 51
Location: sarasota florida

PostPosted: Thu Mar 13, 2008 4:25 pm    Post subject: cayenne pepper Reply with quote

now here is a follow up question.

a. since the pepper is in capsules, it is not hot going in..however, is it tolerable from a stomach/gi upset arena?

b. also, does such a high amount of pepper cause diarrhea or rectal/anal pain/irritation on defecation since the substance p at high doses isnt fully metabolized....i.e, the rectal mucosa has pain fibers just like the mouth, so spicy substance p or capsacin can hurt the mouth as well as the distal end of the alimentary tract.

thank you
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George Rucker
Urology/Urologist
http://prostateconcerns.blogspot.com/
www.urology-partners.com
http://www.cornellurology.com/past-res.html
http://www.lakewoodranchmedicalcenter.com/index.php?&PageID=1088
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HaydnLover
Regular


Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Thu Mar 13, 2008 4:50 pm    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

George,
1stQ:
The only time I've felt any irritation from the pepper would be if I forgot to take it before eating & later took it on a full stomach - then I got a mild heartburn like sensation & from then on always took it before eating with no further stomach problems.
2ndQ:
when I started & was learning how fast to increase the dose I found that if I increased too much, too fast I would get a mild case of diarrhea & it would sting a bit - nothing intolerable. If I got diarrhea from anyother source it would sting.

The major key to taking cayenne is to always take before eating & gradually increase your dose. The body does acclimate to the higher dose.
_________________
72 years old.
2006 biopsy found cancer Gleason score 6 (3+3)
2008 biopsy - no cancer
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goruck
Experienced user


Joined: 22 May 2006
Posts: 51
Location: sarasota florida

PostPosted: Thu Mar 13, 2008 9:43 pm    Post subject: More pepper George Rucker Urologist Reply with quote

I am beginning to research the capsaicin story as much as I can scientifically. I will next turn to the journal of urology which I have special archival access to and search the lab experiments if any available. Your case fascinates me at this point. Best to you haydn and thank you for your frank replies to my questions.




Capsaicin and Cancer


In the U.S., one person dies from cancer each minute, and one out of three people will eventually die from cancer. Normally when the body is injured, cells divide to replace the damaged ones and "know" when to stop dividing. Cancer cells, however, divide uncontrollably and for no obvious reason. Eventually, cancerous growths interfere with normal body functioning, often resulting in death.

Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is the active chemical compound found in the seeds and fruit of chili peppers of the Capsicum genus such as cayenne pepper. This pepper provides numerous health benefits. Capsicum is traditionally used for muscular pain, headaches, to improve circulation and for its gastrointestinal protective effects? It is also commonly added to herbal formulations because it acts as a catalyst for other herbs and aids in their absorption.


Many scientific studies have revealed the exciting potential anti-cancer abilities of capsaicin. Although the exact mechanism(s) is unclear, capsaicin has been shown to induce apoptosis in many different types of cancer cells. Apoptosis is a natural form of cell death that occurs in old or damaged cells that need to be replaced by new, healthier cells.

Capsaicin has been shown to protect the stomach from various types of damage by affecting gastric mucosal blood flow as well as mucosal and bicarbonate secretions. It also has been shown to cause DNA fragmentation and subsequent apoptosis in human gastric adenocarcinoma cells by reducing the expression of a cellular protein that inhibits apoptosis (Bcl-2). Research shows that the number of abnormal cells killed increased with greater doses of capsaicin. According to this study, capsaicin induces apoptosis in abnormal cells by inhibiting NADH-plasma membrane electron transport system by acting as a quinine analog. Cells generate most of the energy (ATP) that they need to survive and reproduce via this electron transport chain, which occurs in the mitochondria (also known as the powerhouse) inside cells. If this system is disrupted, the cell cannot generate enough ATP to sustain itself, and the cell dies. By disrupting the electron transport chain, capsaicin decreases the amount of energy that is available to cancer cells, and these cells cannot continue to proliferate. Cancer cells require more energy than normal cells, because they are growing and dividing more rapidly than normal cells. A reduced supply of energy caused by capsaicin can have a major impact on abnormal cells.

In a recent study conducted at the University of Nottingham, capsaicin was shown to bind to proteins in the mitochondria of abnormal cells and trigger apoptosis without being harmful to surrounding normal cells.

This anti-carcinogenic mechanism is surprisingly similar to how NSP Paw Paw Cell-Reg works.

Dr. Pramod Srivastava and his colleagues conducted a study in which they discovered that capsaicin triggered apoptosis in human pancreatic cancer cells, one of the most difficult types of cancer to treat. Capsaicin increased the number of apoptotic proteins and reduced tumor size in cancerous pancreatic cells but did not negatively affect normal pancreatic cells.

Another study showed that capsaicin inhibited the growth of leukemic cells
possibly by causing an increase in the production of reactive oxygen species inside the abnormal cells, which leads to apoptosis. Capsaicin did not inhibit the growth of normal cells.

Capsaicin has also shown effectiveness in inhibiting ovarian and breast cancer cells in vitro by decreasing the activity of NADH oxidase, an enzyme needed for the production of ATP or cellular energy.

A recent study has shown that capsaicin induced human prostate cancer cells to undergo apoptosis by inhibiting NF-Kappa Beta, a mechanism that leads to the expression of certain genes that are involved in inflammation and the development of cancer. This same study demonstrated that capsaicin slowed prostate cancer cells by regulating androgen receptors on the cells and decreased the production of PSA produced by the abnormal cells.

Recent studies have also demonstrated that capsaicin inhibited the ability of some chemical carcinogens to bind to DNA3, suggesting that capsaicin may have cancer preventative properties.

Capsaicin is generally recognized as safe (GRAS) by the FDA in the United States when used orally and topically in an appropriate manner.8 Capsaicin is found in foods that have a long history of being used in the human diet without harm. This fact lends support to its good safety profile.
Capsaicin and other vanilloid compounds show strong evidence of having promising potential in the fight against many types of cancer. However, more research is needed to determine if capsaicin extracts are safe and effective for use in humans as a treatment or preventative for cancer.

Posted: Friday - February 16, 2007 at 04:57 PM


this was taken from the herb specialist blog by george rucker urologist bradenton, florida
I can direct you to the original post if you query me via my blog below
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George Rucker
Urology/Urologist
http://prostateconcerns.blogspot.com/
www.urology-partners.com
http://www.cornellurology.com/past-res.html
http://www.lakewoodranchmedicalcenter.com/index.php?&PageID=1088
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HaydnLover
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Joined: 09 Mar 2008
Posts: 12
Location: Florida

PostPosted: Thu Mar 13, 2008 11:30 pm    Post subject: Re: Pepper cured my prostate cancer !! Reply with quote

You're preaching to the choir here George - I think it's wonderful stuff!
_________________
72 years old.
2006 biopsy found cancer Gleason score 6 (3+3)
2008 biopsy - no cancer
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