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skin cancers What is this ?

 
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hde357
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PostPosted: Tue Oct 12, 2004 9:52 am    Post subject: skin cancers Reply with quote
Three years ago my nephew had a mole removed from his head (he had this mole his entire life) the mole contained T cells and further tissue removal was necessary. Now at age 7 he went to the dr. to have 2 changing freckles looked at (without knowing his history) the dr. ordered immediate removal... they are being removed today. I am concerned as 3 members of his dads family have had melanoma. I am unable to find any documentation re: children and skin cancer... is it possible?
Thank you
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leo
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Joined: 23 Sep 2004
Posts: 1574
PostPosted: Tue Oct 12, 2004 11:58 am    Post subject: Re: skin cancers Reply with quote
Hi

There have been familial syndromes related to myeloma. Please see excerpts taken from Up-to-Date:

[quote]Some familial cases occur in the setting of the familial atypical multiple mole and melanoma (FAMMM) syndrome, also called the dysplastic nevus syndrome (DNS). This syndrome was originally described in two kindreds in which affected subjects had multiple (over 100) dysplastic (atypical) nevi, and their lifetime cumulative incidence of melanoma approached 100 percent [5,6]. A family history of melanoma in multiple first degree relatives, and younger age at diagnosis are important components of this syndrome. The median age at diagnosis in one series of 23 kindreds was 33, well below that in patients with sporadic melanomas; this difference may be due in part to increased surveillance of subjects from affected families [7]. However, since there is wide clinical variability in the nevus phenotype (such as size and number of moles and degree of irregularity in border and color), there is currently no consensus as to a formal definition of the "atypical mole/melanoma" syndrome.[/quote]

So there is a link, especially in the family that you described. You should have your nephew see a geneticist to be sure.

regards.
Leo
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Disclaimer: this information is for informational purposes only. It is not medical advice.
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