My dad will be finishing his 6th round of monthly Temodar at the end of Sept. We are going for compassionate use of the DCvacine after that. The only problem is that they have to taper off his steroids before they can remove his white blood cells for the procedure as well as during the vaccine injections. He has GBMIV dx in Jan 2011. surgery in Jan as well but was severely set back by the seizure that announced his tumor. He has not responded well to cutting back on the decadron. I am really worried that he won't be able to handle being off decadron. He now walks with a cane but still drags his foot and really doesn't use his right hand much at all.
Are there alternatives for the decadron? Basically the vaccine works by boosting your immune system and steroids are immunosuppressant , complete opposites. The statistics for the DC vaccine seem incredible compared to anything else I've seen. His one good week a month is hard to watch and the thought of the vaccine with its very tiny if any side effects would be great.
Any information would be helpful. I believe he is on 4mg a day and when they tried to bring him down to 2mg a day a couple of months ago, he couldn't speak and was only able to get around in a wheel chair. He slept all day, it was really scary, we thought it was regrowth.