07/08 DX PTCL - NOS, 4B. >50 tumors + BMI.
08/08-12/08 4 cycles CHOEP + 4 cycles GND.
03/09-06/13 Clinical trial of Romidepsin. NED for 64 (28 day) cycles.
07/13 Second relapse with auto-immune symptoms.
08/13 - 02/14 Romidepsin increased, but stopped - lack of response. Nodes resolve spontaneously.
09/14 Third relapse. Nodes appear suddenly.
10/06/14 One cycle Belinostat. Symptoms worsened. Stopped.
10/13/14 Third relapse confirmed. No BMI. Now officially AITL.
10/25/14 Entered trial of Alisertib (MLN8237)
01/05/14 Disease regression + progression. Dr. believes two similar clones at work.
01-12/16-15 Belinostat resumed, leading to Pralatrexate.
"What is faith? It is that which gives substance to our hopes, which convinces us of things we cannot see" Hebrews 11:1