Dx 07/2008 Peripheral T-Cell Lymphoma - Not Otherwise Specified.
Stage 4B, widespread disease, "innumerable" tumors above/below diaphragm + Bone Marrow Involvement.
Primary regimen 4 cycles CHOP+Etoposide plus 4 cycles of Gemcitabine, Navelbine and Doxil.
NED at completion of chemo 12/2008.
Scheduled for salvage therapy of ICE and hospice.
Clinical trial of Romidepsin 03/2009. CR, remained NED for 56 (28 day) cycles.
08/2013 "re-induction" therapy of 3 Romidepsin infusions per 28 day cycle.
Mixed results on 11-01-2013 scans.
Treatment stopped 03-03-2014 due to progression and spleen involvement.
02/2014 Core needle biopsy shows cancer has mutated into AngioImmunoblastic T-Cell Lymphoma.
Additional biopsy scheduled 03/04/2014 to confirm mutation.
"Now, faith is the substance of things to be hoped for, the evidence of things that are not seen" Hebrews 11:1