Radiation Therapy Causes Diabetes?

[Marezie]

First off, my heart felt wishes go out to all who are battling this horrible disease and their caretakers.

About me:

Diagnosed: Stage III Pancreatic Cancer in October 2008
Whipple Surgery: November 14, 2008 (32 days in hospital)
Gemzar Chemo: 6 months just ended July 14th
CA-19-9: Now at 11 (in normal range)
Recent CT Scan: Lungs and Liver clear; lesion on body of pancreas and two (1cm) cysts on tail of pancreas

With the recent CT scan, my Oncologist said not to worry about the lesion and cysts in the pancreas as pancreatic cancer rarely returns in the pancreas. I was to begin radiation/chemo therapy (Xeloda) on Aug 10th. After my consultation with the Radiologist Oncologist this past Monday (Aug 3rd), I was shocked at the risks involved. I asked for time to discuss this with my other doctors and for time to think it over. The issue is that he told me he was going to radiate my entire (remaining) pancreas and that, among the other risks of radiation to the pancreas, I would definitely end up diabetic. It was unknown, however, whether it would be moderate or severe. Except for this cancer, I've always been a healthy person and I don't know how to live otherwise. I'm 60 years old and am in desperate hope to keep this cancer from returning. But I understand that the statistics are against me and that I may not even live 5 years. I'm not sure I want to live those remaining years as a diabetic, reducing my quality of life. I'm confused as to whether the benefits of radiation are worth this new health problem. Can someone help me? In all my research, I have never heard of radiation to the pancreas causing diabetes. Am I overlooking something? Has anyone ever heard of this? And what would YOU do?

Thanks for any help!

[Adagio7780]

Marezie, I am sorry you have been diagnosed with this disease, but happy you have had successful treatment thus far. I am not a doctor but have heard of the diabetes complication as a result of aggressive treatment. My first advice for you is to seek a second opinion regarding the best treatment options for you. You may find a doctor who will spare your pancreas, and you will have to evaluate the risks as best you can.

I have a dear friend who has Type I diabetes and has taken daily insulin injections and multiple-times-daily blood-sugar testing since she was age 3, and she is now 49. This is a pain-in-the-ass part of her daily routine, but she is a wonderful person who has a wonderful husband, and together they have had a terrific life.

I am a 55 year old diagnosed Stage IV in Jan 09. I don't mean to preach, but for the hope of another five years (let alone 25) with diabetes as my main health issue, I would roast my beloved pancreas and feed it to my neighbor's dog.

Good luck in whatever course you decide to take.