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  1. From the paper in discussion: [Emphasis...

    From the paper in discussion:



    [Emphasis mine]

    So before anyone gets too worked up over its potentially negative prognostic value, does anyone know whether or not their PNI+ met this studies...
  2. I would not sweat this, BigAl. My bet is on lab...

    I would not sweat this, BigAl. My bet is on lab sloppiness, but perhaps your PSA had been, say, 0.0199 and popped up 0.001 to 0.020 the day of your test which would wipe out the < sign. No Big Deal...
  3. I would suggest that the key objective is to...

    I would suggest that the key objective is to avoid years of high BP and high LDH. If diet/weight-control does the trick, that's good, but for some it isn't enough.

    Djin
  4. [#73] Dietary Compounds for Targeting Prostate...

    [#73]
    Dietary Compounds for Targeting Prostate Cancer [2019, Review, Full Text]

    https://www.mdpi.com/2072-6643/11/10/2401/htm
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    [#58] Very early continence after radical...

    [#58]
    Very early continence after radical prostatectomy and its influencing factors [2019]

    https://www.frontiersin.org/articles/10.3389/fsurg.2019.00060/abstract
  6. Association of statin use with risk of Gleason score‐specific prostate cancer

    Detailed recent paper on statins and PCa prevention.

    Association of statin use with risk of Gleason score‐specific prostate cancer: A hospital‐based cohort study [2019, Full Text]



    ...
  7. [#72] Association of statin use with risk of...

    [#72]
    Association of statin use with risk of Gleason score‐specific prostate cancer: A hospital‐based cohort study [2019, Full Text]

    https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.2500
  8. [#71] Investigating the Multi-Target...

    [#71]
    Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach [2019, Full Text]
    ...
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    Good care (let alone new medical advances) is...

    Good care (let alone new medical advances) is beyond the reach of much of the population. Many can't get preventive care and present with acute complications (e.g. diabetes, heart disease). Yup, that...
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    I'm hoping the next generations will teach and...

    I'm hoping the next generations will teach and show the older ones what good healthcare is. In the U.S. we've gotten ourselves into an untenable situation where we cannot change an entrenched, broken...
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    Hope you are already feeling better, D2. But...

    Hope you are already feeling better, D2. But don't be shy about speaking up with your docs if you need to. Don't be a martyr with respect to pain or other symptoms.

    Djin
  12. I disagree with the authors: Most Forum...

    I disagree with the authors:



    Most Forum Brothers' RP reports do state the presence or absence of PNI. One of the tables in the paper confirms what I mentioned: some studies show PNI is present...
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    Sounds like you're on track, headed for Station...

    Sounds like you're on track, headed for Station Cure! I'm sure that whatever the inconvenience of the HT, you're feeling better after getting started and choosing your plan. You got yourself to a...
  14. The direct spread of PCa along nerve fibers would...

    The direct spread of PCa along nerve fibers would be manifest as extra-prostatic growth. This would be often revealed at the time of surgery. BCR down the road would IMO be due to EPE+, SM+, and...
  15. ASA, your news article is from 2013. It's POD,...

    ASA, your news article is from 2013. It's POD, postoperative delirium, not dementia. Screening can identify those at risk.

    Quality of recovery in elderly patients with postoperative delirium...
  16. Your doc's opinion about being 0.035 now and...

    Your doc's opinion about being 0.035 now and waiting another 6 months not being a problem was the very point I made earlier today in another thread. You don't need to hit the fire alarm at 0.01,...
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    Hi Steve and Welcome to the Forum. A positive...

    Hi Steve and Welcome to the Forum. A positive surgical margin of 1 mm or less if often not significant, and can sometimes even be an artifact.

    Margins aside, did you have any adverse features...
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    [#91] United States trends in active...

    [#91]
    United States trends in active surveillance or watchful waiting across patient socioeconomic status from 2010 to 2015 [2019]

    https://www.nature.com/articles/s41391-019-0175-9
  19. [#70] Artemisinin and Its Synthetic Derivatives...

    [#70]
    Artemisinin and Its Synthetic Derivatives as a Possible Therapy for Cancer [2018, Review, Full Text]

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872176/

    Flagged by Forum Brother...
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    I understand your concerns, but your prostate may...

    I understand your concerns, but your prostate may not cooperate with your hopes and plans. You can ask about radiation treatment, but I have my doubts about good BPH outcomes with it.

    As a rule,...
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    Congrats on reaching a treatment decision! Look...

    Congrats on reaching a treatment decision! Look through Forum threads on Before and After RP tips.

    Looking forward to hearing only good things going foward!

    Best,

    Djin
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    Hi lj, A few points for your consideration: ...

    Hi lj,

    A few points for your consideration:


    I had a TURP in 2013 for BPH which was a complete success. I had had negative biopsies before and after. In 2017 a biopsy found Gleason 10 PCa. I...
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    Setting aside whether this treatment actually...

    Setting aside whether this treatment actually does anything (I've not come across studies after the 2017 study above), the point of the IV route is to administer a pharmacological dose to wayward...
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    When you take Vit. C, any excess is quickly...

    When you take Vit. C, any excess is quickly eliminated in your urine, so its concentration in the blood and, consequently, its bioavailability at the cellular level in tissue will be low. Putting it...
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    There is ample literature that this information...

    There is ample literature that this information is not accurate:

    Management of Biochemical Recurrence after Primary Curative Treatment for Prostate Cancer: A Review [2018, Full Text]


    ...
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