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  1. Yes, we've seen other studies highlighting this....

    Yes, we've seen other studies highlighting this. If I remember, the longer the therapy, the greater the risk. I wonder if we'll see an increase in intermittent, rather than continuous, HT, especially...
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    Hi mostth. The HT will make the adjuvant RT all...

    Hi mostth. The HT will make the adjuvant RT all the more effective at getting the PCa that was left behind. Those 24 negative nodes were a welcome indication that all the culprits are local and easy...
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    Busby needs to be concerned with his persistent...

    Busby needs to be concerned with his persistent and rising PSA and what treatment is best right now. BCR by 5 yr isn't germain (he is essentially at 0.2 and rising right now!). BCR is a return of,...
  4. If you scroll halfway down a bit here...

    If you scroll halfway down a bit here, you'll see the branches off the right and left prostatic artery and deliver blood to each side of the prostate. I believe the vascular bed in the case of...
  5. I think the "recurrence rt. semi vascular bed" is...

    I think the "recurrence rt. semi vascular bed" is correct.

    Djin
  6. [#138] Shared decision making for men facing...

    [#138]
    Shared decision making for men facing prostate cancer treatment: a systematic review of randomized controlled trials [2019, Review, Full Text]
    ...
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    [#112] Radiotherapy In The Definitive Management...

    [#112]
    Radiotherapy In The Definitive Management Of Oligometastatic Prostate Cancer: The Johns Hopkins Experience [2019, Full Text]

    https://www.redjournal.org/article/S0360-3016(19)33641-7/pdf
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    Note the important stats from the 1-yr biopsies:...

    Note the important stats from the 1-yr biopsies:

    Profound Medical Announces Positive Topline Results from TACT Pivotal Clinical Trial of TULSA-PRO® in Patients with Prostate Cancer [2019]
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    Absolutely!

    Absolutely!
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    Congrats on your surgery, wbigs! Walking (without...

    Congrats on your surgery, wbigs! Walking (without overdoing it) is great for recovery in general and for moving gas out, too. Shorter, more frequent is better than longer, less often at first.

    Djin
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    The message from the studies on HT's side...

    The message from the studies on HT's side effects is that exercise is the number one way to keep them at their minimum.

    Djin
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    Do not worry about the 10 days, Busby, just enjoy...

    Do not worry about the 10 days, Busby, just enjoy them!

    Djin
  13. Research landscape of liquid biopsies in prostate cancer [Review]

    Research landscape of liquid biopsies in prostate cancer [2019, Review, Full Text]

    A recent major review.



    [Emphasis mine]
  14. [#134] Research landscape of liquid biopsies in...

    [#134]
    Research landscape of liquid biopsies in prostate cancer [2019, Review, Full Text]

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682718/
  15. Salvage reirradiation for local prostate cancer...

    Salvage reirradiation for local prostate cancer recurrence after radiation therapy. For who? When? How? [2019, Brief Communication]
  16. Several of the treatment modalities have poor...

    Several of the treatment modalities have poor long-term toxicities.

    Note that there is a Caveats section in the link.

    Djin
  17. Nonsurgical Salvage Local Therapies for Radiorecurrent PC: Review & Analysis

    Nonsurgical Salvage Local Therapies for Radiorecurrent Prostate Cancer: A Systematic Review and Meta-analysis [2019, Full Text]

    This came up as new in a search engine today, but it's from Jan. of...
  18. [#181] Salvage reirradiation for local prostate...

    [#181]
    Salvage reirradiation for local prostate cancer recurrence after radiation therapy. For who? When? How? [2019, Brief Communication]
    ...
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    [#36] Salvage Local Treatments After Focal...

    [#36]
    Salvage Local Treatments After Focal Therapy for Prostate Cancer [2019, Review, Full Text]

    https://euoncology.europeanurology.com/article/S2588-9311(19)30042-2/fulltext
  20. Hi Davefr. One of your biopsied cores was G7...

    Hi Davefr. One of your biopsied cores was G7 (3+4) with 45% Grade 4. It's not unreasonable to think that there may currently be lesions where the Grade 4 component predominates. If that is the case,...
  21. [#180] The impact of the definition of...

    [#180]
    The impact of the definition of biochemical recurrence following salvage radiotherapy on outcomes and prognostication in patients with recurrent prostate cancer after radical prostatectomy: a...
  22. The definition of SECOND biochemical recurrence (after RP AND SRT)

    In today's Prostate Cancer News:

    The definition of SECOND biochemical recurrence (after prostatectomy AND salvage radiation)



    From the study cited:
  23. Hi jerry. I think you've made a good...

    Hi jerry.

    I think you've made a good decision, especially at your age. That upward-trending PSA did not bode well at all, as your G9 (4+5) biopsy cores proved. A G9 warrants what you've done -- a...
  24. [#133] Impact of biopsy perineural invasion on...

    [#133]
    Impact of biopsy perineural invasion on the outcomes of patients who underwent radical prostatectomy: a systematic review and meta-analysis [2019, Review]

    Impact of biopsy perineural...
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    Yes, distant metastases are those outside the...

    Yes, distant metastases are those outside the pelvis. They can be treated with HT; depending on the location, some can be irradiated.

    Multiple positive surgical margins, however, is an indication...
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