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Thread: What I Need to Know About About Prostate Biopsy

  1. #161
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    Quote Originally Posted by Southsider View Post
    I don't think that's good at all- did you call your doctor about this? fever means infection and the antibiotics are supposed to prevent that.
    In both cases, I was admitted for observation since I have a history of endocarditis. Yes I worked with my infectious disease doctor in both cases and blood cultures were negative both times. Itís a rare case but Iíve been given clearance for future biopsies. This stress however is way worse than the biopsy itself.

  2. #162
    Quote Originally Posted by Southsider View Post
    I don't think that's good at all- did you call your doctor about this? fever means infection and the antibiotics are supposed to prevent that.
    Antibiotic resistance is becoming a problem, too. Here's a novel preventive using something similar to betadine/iodine:
    "Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection"
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692615/
    Gathering info for a family member: 63, good general health, UTI/prostatitis/103Fever/septicemia led to finding nodule via DRE. 3T MRI scheduled for October. PSA dropped from 27 at ER to 15 at five days later, after the IV Abx and then cephalexin.

  3. #163
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    Hi everyone. New guy here. My PSA has bounced around for several years and my most recent bloodwork was a 6. This morning doc ordered a biopsy a couple weeks out. I am worried to death about this procedure. I plan to insist on valium at a minimum. The discomfort and potential pain from the procedure worry me more than the results. I would welcome any encouraging words. Thanks.

  4. #164
    Moderator Top User HighlanderCFH's Avatar
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    Hi Gard,

    Welcome aboard -- with hopes that you won't need to become a member.

    Although we hear horror stories about the experiences some of us have had with prostate biopsies, the vast majority of them take place without incident -- and there are many thousands being performed every day.

    I am an accomplished medical coward and was very fearful of the anticipated pain, etc. But, as long as you have an experienced urologist -- who also numbs the rectum and prostate -- you will "hear" the procedure more than you will feel it. Just think of it as a 20 minute digital rectal exam -- uncomfortable & awkward, but not really painful.

    As scared as I was, I did not need anything to calm me down. I just endured the procedure after promising myself that I would simply plan on NOT enjoying those 20 minutes. As it turned out, I did not enjoy the experience -- but was NOT overcome with terrible pain either.

    For me, there were no complications or pain, blood, etc, afterward.

    And I hope for the same experience for you.

    Good luck -- including the results!
    Chuck
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections without "training wheels," usable erections with 100mg Sildenafil.
    NOTE: ED caused by BPH, not the surgery.

  5. #165
    Gard, two point. For the majority of men, the biopsy turns out to be No Big Deal. Ask your doc for a nerve block--and a pill as long as someone else drives you. Second, for the immediate future, biopsy will remain the only way to diagnose prostate cancer.
    69 yr at Dx, BPH x 20 yr, 9 (!) neg. Bx, PCA3 -
    7-05-13 TURP (90→30 g) path neg. then 6-mo. checks
    6-06-17 Nodule on R + PSA rise on finasteride: 3.6→4.3
    6-28-17 Bx #10: 2/14 cores: G10 (5+5) 50% RB, G9 (4+5) 3% RLM
    Bone scan, CTs, X-rays: neg.
    8-7-17 Open RP, neg. frozen sections, Duke Regional
    SM EPE BNI LVI SVI LNI(16): negative, PNI+, nerves spared
    pT2c pN0 pMX acinar adenocarcinoma G9 (4+5) 5% of prostate (4.5x5x4 cm, 64 g)
    11-10-17 Decipher 0.37 Low Risk: 5-yr met risk 2.4%, 10-yr PCa-specific mortality 3.3%
    Dry; ED OK with sildenafil
    9-16-17 (5 wk) PSA <0.1
    LabCorp uPSA, Roche ECLIA:
    11-28-17 (3 m ) 0.010
    02-26-18 (6 m ) 0.009
    05-30-18 (9 m ) 0.007
    08-27-18 (1 yr.) 0.018 (?)
    09-26-18 (13 m) 0.013 (30-day check)
    11-26-18 (15 m) 0.012
    02-25-19 (18 m) 0.015
    05-22-19 (21 m) 0.015
    08-28-19 (2 yr. ) 0.016
    Avg. = 0.013

  6. #166
    Top User
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    Quote Originally Posted by Gard View Post
    Hi everyone. New guy here. My PSA has bounced around for several years and my most recent bloodwork was a 6. This morning doc ordered a biopsy a couple weeks out. I am worried to death about this procedure. I plan to insist on valium at a minimum. The discomfort and potential pain from the procedure worry me more than the results. I would welcome any encouraging words. Thanks.
    Good to hear you're not afraid of the result. The result is the tough part. It lasts forever. You will forget the pain and discomfort in a few days.

  7. #167
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    Sep 2018
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    Chuck:

    Thanks for your thoughts. I got the results back and all cores were negative. With my family history I was expecting the worst. So my question for anyone is how common is a PSA pushing 7/8 to be negative? Thanks.

  8. #168
    Quote Originally Posted by Gard View Post
    Chuck:

    Thanks for your thoughts. I got the results back and all cores were negative. With my family history I was expecting the worst. So my question for anyone is how common is a PSA pushing 7/8 to be negative? Thanks.
    Congratulations.

    I would look at some of the herbs that address prostate health.

    You are fortunate.
    At age 55, PSA 22, Gleason: 9 (4+5), 8(4+4), 7(3+4), 6(3+3)
    8 out of 12 cores positive
    DaVinci 14 October 2014
    Pathology of surrounding tissue samples was negative, though they annotated it as stage 3.
    Post surgery PSA:
    Jan 2015 <0.04
    2016 <0.04
    2017 0.05
    2018 0.1


    In 2018; 45 radiation treatments and hormone treatment [with Lupron for the next 2 years].
    In 2019; on Lexapro to deal with the Lupron.

  9. #169
    I know several men, including my 58 yo nephew, who have had PSA over 8 for ten years or more. Multiple biopsies have been negative. Itís fairly common. But, you canít just walk away and ignore it. You need to have a urologist and do PSA or PHI/4K/PCA3 tests at least once a year.

  10. #170
    Senior User
    Join Date
    Aug 2017
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    If your PSA stays under 10, the odds are in your favor but not without some degree of risk. Take a look at this study which addresses it:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186957/

 

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