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Thread: What I Need to Know About HT

  1. #1
    Moderator Top User HighlanderCFH's Avatar
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    What I Need to Know About HT

    Quote Originally Posted by white08gt View Post
    got my Eligard shot in the stomach the 12th of June and have every side effect mentioned. some are worse than others. is this the same as Lupron, just another maker? this is not helping with manhood returning.
    Probably a good idea to have a sticky on HT since we have them on other treatments. I looked to see if there was an old HT sticky from the past (I cut back on a lot of stickies a few months ago), but can't seem to find one.

    So I'll create one and hopefully you, and others, will put in pertinant information & experiences to help those who may be considering this treatment option.

    Thanks for the suggestion,
    Chuck
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections without "training wheels," usable erections with 100mg Sildenafil.
    NOTE: ED caused by BPH, not the surgery.

  2. #2
    Experienced User
    Join Date
    Dec 2013
    Posts
    69
    Here are my reactions about 2 months after a shot of Lupron and Casodex. The shot is every 3 mos and daily Casodex. so far not so bad. Some hot flashes, mainly at night, causing lots of tossing and turning. Some loss of energy, maybe some memory loss and headaches. Zero sex interest....worst is trying to stay asleep at night.

    The effects come on gradually, and many say keep getting worse...Am not into exercising at all, but do stay active. Wife and I she has non Hodgkins lymphoma) take lots of naps.

    The shot was given in my upper butt, no big deal either. I guess the phrase "your results may vary" applies to HT. I just hope it works as promised, my PSA has been RISING into double digits after surgery.

    Next PSA test will determine further more aggressive treatments. Maybe my luck will change.
    Last edited by mikem350; 08-03-2014 at 03:18 PM.
    Diagnosed (10/2013). Gleason 8 x2, gland 60g
    DaVinci RP performed 1-20-14, age 65

    Contained in capsule, one side nerves spared
    Clean lymph nodes and borders, clean path report of surroundings
    Aggressive G8 Ductal cancer found

    Post surgery PSA climbing, from 8.2 (5 weeks) to 11.6 (13 weeks)

    Started hormone therapy/ADT, Lupron, Casodex daily 5-22-14
    PSA has been undetectable: smile:
    Considering salvage radiation

  3. #3
    Experienced User
    Join Date
    Aug 2013
    Posts
    87
    8 months in of Casodex and 7 of Lupron, few side affects for my husband. A few hot flashes a day, slight increase in man boobs, no weight gain to due his intensive, aggresive exercise and eating plan. No fatigue or mood change. Even tho med onc was skeptical about Cialis/Viagara, the little helpers are working just fine a couple of times a week (no ejaculation, of course). Though he does report that he no longer THINKS about sex all the time. But last month he hit the ZERO CLUB so we are giddy. Oddly we are happier than we have ever been. While waiting for other cancer shoes to drop, we are doing a lot of travelling. Look forward to reading and following other posts on this sticky.
    Married 5 yrs, I'm 64 he's 69
    August 2013, initial Rx T1c
    DRE negative, CT & bone scans inconclusive
    PSA 147/103 (one wk apart)
    8/12 cores positive, 6 Gleason 7; 2 Gleason 6
    21% of total cores positive
    9/30 ultrasound revealed cancer in anterior of prostate
    October petScan/ MRI 1 cm lesion on sacrum DX stage 4
    curative approach tho slim chance it is curable
    12/15/13 Casodex started;50 mg daily
    1/15/14 PSA drops 39.7
    1/22/14 Lupron 22.5/3-month injection;5 mg daily Cialis
    4/14/14 PSA .1 Yay
    7/10, 10/2, 12/26/14 zero club. <.1 Viagra still working!
    1/22/15 bone scans--no change in mets on sacrum; said no thanks to radiation
    6/15/15 HT HOLIDAY. Yay.
    9/12/15 zero club, return of chest hair! And orgasms.
    12/15 uck. PSA 4
    1/16 PSA at 8.6. Back to Casodex/Lupron
    2/16 PSA .6 then <.1 by May
    12/16 starting 2nd HT Holiday!
    5/17 viagara-free sex and orgasms
    6/17 PSA 3.2. HOLIDAY over, back on Casodex

  4. #4
    Moderator Top User HighlanderCFH's Avatar
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    I'll be hoping & praying that he stays in the Zero Club and that those other cancer shoes never drop.

    Take care,
    Chuck
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections without "training wheels," usable erections with 100mg Sildenafil.
    NOTE: ED caused by BPH, not the surgery.

  5. #5
    Senior User
    Join Date
    Apr 2014
    Posts
    127
    i received my Eligard 6 month shot in the stomach, a little painfull. started hot flashes right away, aching and shrinking testes in the first month. tender breasts after working out and restless nights waking up sweating. the good news is my PSA after surgery went from 0.10 at 4 months to 0.05 30 days after HT. start my salvage radiation on August 11th. sex drive is zero, still think about it but Lil Elvis has left the building. have gained 10 lbs. since HT started and no energy to workout, cut down to 1 hour a day everyother day down from 5 days a week for 1.5-2 hours. i do 10-12 reps 4 sets going up 5-10 lbs each set and not being able to go up weight every other week. just struggling to keep my weights that i had worked up to. my wife says i am going through menopause, welcome to their world.

  6. #6
    Regular User
    Join Date
    Aug 2009
    Posts
    38
    Hi:- I suggest that people considerung HT start off with reading Pat Walsh's "Guide to Surviving Prostate Cancer", chapter 12 on androgen deprivation. Most HT being eye-wash, pretty disillusioning, just big business of phamaceutical industry and the medical establishment. Pat Walsh, pioneer in nerve-sparing surgery, associated with Johns Hopkins.
    Reinardo
    Diagnosed in 2001 at PSA 8.9 Gleason 2+3
    Triple Hormone Therapy (Leibowitz) in 2002
    Active Surveillance thereafter

    Palliative TUR-P in 12-2009

  7. #7
    ADT or HT or Hormone Therapy, it's all the same thing, Chemical Castration. It's as simple as that...It costs a lot more than physical castration and sometimes it's not as effective. If your time on ADT is only temporary, an adjunct treatment to radiation, then when you stop taking the drugs your testosterone should return to normal and the effects are reversed. But after 3 or more years on the drugs, the effect tends to become permanent..

    So what are the "side-effects"? Well they add up to the heaviest load of quality of life changes associated with prostate cancer treatment..In exchange for controlling your incurable cancer, they transform you into a eunuch...The list of physical changes is well known and easy to look up... But given the benefit most men receive, most men choose the life extension HT provides....When HT is administered to men over 65, the effects are hot flashes, loss of most body hair, loss of sex drive and ability, weight gain, fatigue, loss of muscle and bone mass, the whole package...
    PSA at age 55: 3.5, DRE negative.
    65: 8.5, DRE " normal", biopsy, 12 core, negative...
    66 9.0 DRE "normal", BPH, (Proscar)
    67 4.5 DRE "normal" second biopsy, negative.
    67.5 5.6, DRE "normal" U-doc worried..
    age 68, 7.0, third biopsy (June 2010) positive for cancer in 4 cores, 2 cores Gleason 6, one core Gleason 7. one core Gleason 9. RALP on Sept. 3, 2010, Positive margin, post-op PSA. 0.9, SRT , HT. Feb.2011 PSA <0.1 Oct 2011 <0.1 Feb 2012 <0.01 Sept 2012 0.8 June 2013 1.1, Casodex added, PSA 0.04 10/2013. PSA 0.32 1/14. On 6/14 PSA 0.4, "T"-5. 10/14 PSA 0.6, T-11. 1/2015 PSA 0.106. 4/15. 0.4, 9/15 1.4, 3/16 Zytiga, 0.04, 5/17 1.4 may switch to Xtandi. 3/1/2018. PSA now 54, chemo will begin next month. 7/19, PSA 2000 starting Lu-177 tomorrow..77 years old now..

  8. #8
    Has anyone in the club who had their PSA return after surgery, opted for HT rather than radiation? If so why based on side affects.
    Allen

  9. #9
    Senior User
    Join Date
    Apr 2014
    Posts
    127
    usually do a combo of both, at least with me. i have finished my salvage radiation, 8 weeks. was not bad at all, the HT as been worse on me than SR. i would take radiation over HT anyday. say good by to the twins, breast pain, retaining fluid, belly fat and no energy from zero testostrone. i am Eligard 6 month shot, almost 5 months in and can still feel the knot in my stomach where i got the shot. not exactly painless, hugh needle and bleed pretty good afterwards. no sex drive and can't even if i wanted to, just i was regaining my form the HT killed it. radiation is a piece of cake.

  10. #10
    Radiation can still achieve a cure if surgery failed to do so...HT by itself is palliative..It can control the cancer for a while but it offers no cure....The best success in treating advanced PC comes from combination treatments...
    PSA at age 55: 3.5, DRE negative.
    65: 8.5, DRE " normal", biopsy, 12 core, negative...
    66 9.0 DRE "normal", BPH, (Proscar)
    67 4.5 DRE "normal" second biopsy, negative.
    67.5 5.6, DRE "normal" U-doc worried..
    age 68, 7.0, third biopsy (June 2010) positive for cancer in 4 cores, 2 cores Gleason 6, one core Gleason 7. one core Gleason 9. RALP on Sept. 3, 2010, Positive margin, post-op PSA. 0.9, SRT , HT. Feb.2011 PSA <0.1 Oct 2011 <0.1 Feb 2012 <0.01 Sept 2012 0.8 June 2013 1.1, Casodex added, PSA 0.04 10/2013. PSA 0.32 1/14. On 6/14 PSA 0.4, "T"-5. 10/14 PSA 0.6, T-11. 1/2015 PSA 0.106. 4/15. 0.4, 9/15 1.4, 3/16 Zytiga, 0.04, 5/17 1.4 may switch to Xtandi. 3/1/2018. PSA now 54, chemo will begin next month. 7/19, PSA 2000 starting Lu-177 tomorrow..77 years old now..

 

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