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Thread: OT: Heart issues and Diet

  1. #11
    WOW!!! Otago, PhD!!! Great job! Excellent points and all well taken!

    As human beings there are a myriad # of variables (both known and unknown) that impact our overall health status. Many of which have cumulative total effects over many decades of our lives. Also, as a human being, I strongly believe that as individuals we have a responsibility to control those variables that we are capable of controlling!

    I am a firm advocate of Healthy Lifestyles: "Healthy diet, regular exercise, healthy weight, activities that challenge one's cognitive skills, belief in the Greater Power, relaxation and fun!

    PBS is truly "Non-Profit" (they don't pay taxes) BUT the MDs that appear and pitch their Dietary Programs are anything but! Many of these, such as Dr Fuhrman's programs seem to be aimed at the already obese, flaccid population with Type II diabetes.

    The food industry has been destructive in the creation of "industrial" fats and the infusion of sugar into nearly everything. Thus the consumer must be vigilant.

    The Greatest, Most Esoteric and Profound Nutritional Scientist in history of the world was Herbert Khaury.

    He summarized the essence of this modern day nutritional argument so succinctly:

    "You are What You Eat"

    Quote by Herbert Khaury (aka Tiny Tim!!!)

    Thus: Eat Well, Live Well, Enjoy Life!

    MF
    Last edited by Michael F; 02-17-2016 at 03:53 PM.
    PSA: Oct '09 = 1.91, Oct '11 = 2.79, Dec '11 = 2.98 (PSA, Free = 0.39ng/ml, % PSA Free = 13%)
    Referred to URO MD
    Jan '12: DRE = Positive: "Left induration"
    Jan '12: Biopsy = 6 of 12 Cores were Positive: 1 = G7 (3+4) and 5 = Gleason 6
    Referred to URO Surgeon
    March '12: Robotic RP: Left: PM + EPE. MD waited in surgery for preliminary Path Report then excised substantial left adjacent tissue(s) down to negative margins and placed 2 Ti clips for SR guidance, if needed in future.
    Pathology: Gleason (3+4) pT3a pNO pMX pRO c tertiary pattern 5 / Prostate Size = 32 grams / Tumor = Bilateral: 20% / PNI: present
    3 month Post Op standard PSA = <0.1 ng/ml
    1st uPSA at 7 months Post Op = 0.018 ng/ml
    uPSA remains "stable" at 84 Months Post Op: Mean = 0.021 (20x uPSAs: Range 0.017 - 0.026) LabCorp: Ultrasensitive PSA: Roche ECLIA
    Continence = Very Good (≥ 99%)
    ED = present

  2. #12
    Administrator Top User Didee's Avatar
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    Brilliant response, Otago.

    The main reasons why diet discussions do get shut down here is due to all the hype about new fail safe diets and members wishing to push their own ones as they feel they are working for them (which no one is doing in this thread)

    My feeling is that we have to do what we feel is best for us, do the research which, as Otago points out is often contradictory and out to sell to make money. It all changes so much, no wonder everyone is confused. I like Otago's running backwards analogy. One I like to quote is " I drink (insert a name of a juice or food item) every morning, Have done for the last two years and have not had a car accident, therefore (preferred juice, food item) prevents car accidents.

    We are running a similar gauntlet here with hubby's advanced liver disease from Ulcerative Colitis as a teenager. He was on the liver transplant list but is now stable with stent replacement every 3 months. His liver processes protein and fat 18% more than ours so this has to be upped and protein every two hours plus prescribed protein drinks through the night. Trying to do what is best for him is also difficult. Liver team and dietitian do help with advice but then advice can change. Sighhhhh
    Aussie, age 61
    1987 CIN 111. Cervix lasered, no further problems.

    Years of pain, bleeding, women's plumbing problems. TV ultrasound, tests, eventual hysterectomy 2007, fibroids in lining of Uterus.

    Dx Peripheral T Cell Lymphoma stage 2B bulky, aggressive Dec/09.
    6 chop14 and Neulasta.
    Clean PET April/10, 18 rads 36gy mop up. All done May 2010
    Iffy scan Nov. 2011. Scan Feb 2012 .still in remission.Still NED Nov 2012.
    Discharged Nov 2014.

    May/2012. U/sound, thyroid scan, FNB. Benign adenoma.

    Relapse Apr 2016. AITL. Some chemos then on to allo transplant. Onc says long remission was good. Still very fixable.

    SCT Aug 2016

  3. #13
    Didee, thanks to you, and you too Chuck, for being tolerant and recognizing that intelligent discussion of diet is relevant to all diseases, even if this one is focused on Heart Disease.
    I truly hope your husband remains stable, and gets the liver when he needs it.
    Diagnosed at age 64 (in November, 2014), PSA 4.3
    Nov 2014 BX 3 of 12 cores positive original pathology G8. Johns Hopkins second opinion, G6
    Surgery with Dr Ash Tewari Jan 6, 2015
    Post surgical pathology, stage T2c, bilateral disease, upstaged to G7(3+4)
    5% of Prostate involved in Tumor. Organ confined, Margins, SV, lymph nodes (9) all negative, PNI positive
    PSA <.02 until (uh-oh), 2/17 .02. Then 5/17-.033, 8/17-.033, 11/17-.046, 4/18-.060, 6/18-.068, 7/18- .082, 8/18-. 078.
    Decipher score low risk, .37
    ADT/Firmagon started August 2018. SRT to start SEPT 2018. Finished SRT November 2018, Finished ADT Feb 2019
    T=7, PSA <.05

  4. #14
    Otago i read your response again, tonight, after work,and i admire your knowledge and tenacity, and the thought you have put into this.
    I actually have asked on the Davis website - can you point me to the science that shows this is real. My query is welcome, but i am pointed to citings in the Cureality Guide. They dont seem like scientific studies, and dont seem like big picture issues are addressed.

    Seprately, the approach Dr Goodman takes just seems to make sense to me. Do the advanced bloodwork, and it MAY well tell us what will work for you and what wont. What foods and meds will help you and what won't. Its a logical approach. And by the way, to your point, he was quite honest when i met with him. He spoke with confidence about his approach, but stated that there are those that will disagree with him, and its possible he could be wrong about certain things. But he feels after 30 years in the game, he has a lot of knowledge and his approach is valid. I liked that.

    BTW, i got the first two tests results back today, one was the Magnesium, which as you know he talks about alot, and it came back smack in the middle of the normal range. The other was blood mercury and it came back at 9, whereas under 10 is considered in range, so high end. Dont recall if i had seafood the night before which you are supposed to avoid. In any case, i dont know what the mercury level means, in terms of possible treatment.
    These two tests were done at Quest and came back quickly. The more specialized tests are being done at Boston Heart Diagnostics as i mentioned, and will take a few weeks.

    In any case, as i said earlier, i will continue to research, and learn. I have a feeling i may be looking for facts, where facts dont exist, only educated opinions.

    BTW, Otago, if you want to converse about this off the forum for our mutual benefit, i would be happy to. If so, just Private Message me and i will provide you with my email address.
    Thanks again for sharing your thoughts in such a detailed, well thought out way.
    Diagnosed at age 64 (in November, 2014), PSA 4.3
    Nov 2014 BX 3 of 12 cores positive original pathology G8. Johns Hopkins second opinion, G6
    Surgery with Dr Ash Tewari Jan 6, 2015
    Post surgical pathology, stage T2c, bilateral disease, upstaged to G7(3+4)
    5% of Prostate involved in Tumor. Organ confined, Margins, SV, lymph nodes (9) all negative, PNI positive
    PSA <.02 until (uh-oh), 2/17 .02. Then 5/17-.033, 8/17-.033, 11/17-.046, 4/18-.060, 6/18-.068, 7/18- .082, 8/18-. 078.
    Decipher score low risk, .37
    ADT/Firmagon started August 2018. SRT to start SEPT 2018. Finished SRT November 2018, Finished ADT Feb 2019
    T=7, PSA <.05

  5. #15
    Super Moderator Top User po18guy's Avatar
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    What we want and need is not necessarily discussion, but results. Check back, all of those who have altered their diets and let us know the good, the bad and the ugly. IOW, show us the money!

    What we want to avoid is the marathon-multi-post theorems/manifestos such as one I nuked recently in which the poster claimed that it was our immune systems causing cancer. It sounded PBS impressive, but there was max agenda and zero science behind it.
    05/08-07/08 Tumor appears behind left ear. Followed by serial medical incompetence on the parts of PCP, veteran oncologist and pathologist (misdiagnosis via non-diagnosis). Providential guidance to proper care at an NCI designated comprehensive cancer center.
    07/08 Age 56 DX 1) Peripheral T-Cell Lymphoma-Not Otherwise Specified. Stage IV-B, >50 ("innumerable") tumors, bone marrow involvement.
    08/08-12/08 Four cycles CHOEP14 + four cycles GND (Cyclofosfamide, Doxorubicin, Vincristine, Etoposide, Prednisone & Gemcitabine, Navelbine, Doxil)
    02/09 2) Relapse.
    03/09-06/13 Clinical trial of Romidepsin > long-term study. NED for 64 twenty-eight day cycles, dose tapered.
    07/13 3) Relapse, 4) Suspected Mutation.
    08/13-02/14 Romidepsin increased, stopped for lack of response. Watch & Wait.
    09/14 Relapse/Progression. Visible cervical nodes appear within 4 days of being checked clear.
    10/06/14 One cycle Belinostat. Discontinued to enter second clinical trial.
    10/25/14 Clinical trial of Alisertib/Failed - Progression.
    01/12/15 Belinostat resumed/Failed - Progression. 02/23/15
    02/24/15 Pralatrexate/Failed - Progression. 04/17/15
    04/15 Genomic profiling reveals mutation into PTCL-NOS + AngioImmunoblastic T-Cell Lymphoma. Stage IV-B a second time. Two dozen tumors + small intestine (Ileum) involvement.
    04/22/15 TEC (Bendamustine, Etoposide, Carboplatin). Full response in two cycles. PET/CT both clear. Third cycle followed.
    06/15-07/15 Transplant preparation (X-rays, spinal taps, BMB, blood test, MUGA scan, lung function, CMV screening, C-Diff testing etc. etc. etc.) Intrathecal Methotrexate during spinal tap.
    BMB reveals 5) 26% blast cells of 20q Deletion Myelodysplastic Syndrome MDS), a bone marrow cancer and precursor to Acute Myeloid Leukemia.
    07/11-12/15 Cyclofosfamide + Fludarabine conditioning regimen.
    07/16/15 Total Body Irradiation.
    07/17/15 Moderate intensity Haploidentical Allogeneic Stem Cell Transplant receiving my son's peripheral blood stem cells.
    07/21-22/15 Triple dose Cyclofosfamide + Mesna, followed by immunosuppressants Tacrolimus and Mycophenolate Mofetil.
    07/23-08/03/15 Marrow producing zero blood cells. Fever. Hospitalized two weeks.
    08/04/15 Engraftment occurs, and blood cells are measurable - released from hospital.
    08/13/15 Day 26 - Marrow is 100% donor cells. Platelets climbing steadily, red cells follow.
    09/21/15 Acute skin Graft versus Host Disease arrives.
    DEXA scan reveals Osteoporosis.
    09/26/-11/03/15 Prednisone to control skin GvHD.
    11/2015 Acute GvHD re-classified to Chronic Graft versus Host Disease.
    05/2016 Tacrolimus stopped. Prednisone from 30-90mg daily tried. Sirolimus begun. Narrow-band UV-B therapy started, but discontinued for lack of response. One treatment of P-UVAreceived, but halted due to medication reaction.
    09/16/16 Three skin punch biopsies.
    11/04/16 GvHD clinical trial of Ofatumumab (Arzerra) + Prednisone + Methylprednisolone begun.
    12/16 Type II Diabetes, Hypertension - both treatment-related.
    05/17 Extracorporeal Photopheresis (ECP) begun in attempt to control chronic Graft-versus-Host-Disease (cGvHD. 8 year old Power Port removed and replaced with Vortex (Smart) Port for ECP.
    05/2017 Chronic anemia (low hematocrit). Chronic kidney disease. Cataracts from radiation and steroids.
    06/17 Trying various antibiotics in a search for tolerable prophylaxis.
    08/17 Bone marrow biopsy reveals the presence of 2% cells with 20q Deletion Myelodysplastic Syndrome, considered to be Minimum Residual Disease.
    12/17 Bone marrow biopsy reveals no abnormalities in the marrow - MDS eradicated. The steroid taper continues.
    01/18 Consented for Kadmon clinical trial.
    03/18 Began 400mg daily of KD025, a rho-Associated Coiled-coil Kinase 2 Inhibitor (ROCK2).
    09/18 Due to refractory GvHD, Extracorporeal Photopheresis halted after 15 months ue to lack of additional benefit.
    10/18 I was withdrawn from the Kadmon KD025 clinical trial due to increasing fatigue/lack of benefit.
    11/18 Began therapy with Ruxolitinib (Jakafi), a JAK 1&2 inhibitor class drug. Started at half-dose due to concerns with drug interactions.

    To date: 1 cancer, relapse, second relapse/mutation into 2 cancers, then 3 cancers simultaneously, 20 chemotherapy/GVHD drugs in 11 regimens (4 of them at least twice), 5 salvage regimens, 4 clinical trials, 5 post-transplant immuno-suppressant/modulatory drugs, the equivalent of 1,000 years of background radiation from 40+ CT series scans and about 24 PET scans.
    Both lymphoid and myeloid malignancies lend a certain symmetry to the hematological journey.

    Believing in the redemptive value of suffering makes all the difference.

  6. #16
    Moderator Top User HighlanderCFH's Avatar
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    You're welcome, Prato.

    And wishing the best for your husband, Di.
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections without "training wheels," usable erections with 100mg Sildenafil.
    NOTE: ED caused by BPH, not the surgery.

  7. #17
    Senior User
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    I've been following this discussion and guess I will put my 2 cents worth in.
    I am recovering from quadruple heart bypass surgery at this time. Prior to my release from the hospital a dietitian that specializes with heart patients came in and spoke with my wife and I at length. She said everyone is different and went over specifically what diet changes I should be making. She was able to see blood reports etc. for my particular problem. First and foremost I need to loose the salt shaker. RDA for sodium is 2000mg. Watch portion control, loose some weight and exercise on a regular basis. Well, the exercise isn't a problem as I was doing that anyway. The salt and portion control is something else.
    However, in the hospital I was on a salt free diet and it really wasn't to bad after the first couple of days. To me my biggest problem is portion control. I was raised that if it is on the plate you eat it all. That had to change. Ref. salt in food, read the label, according to the dietitian if a label has more that 400mg of salt, don't buy it. My wife has been watching the portion control and salt content of foods and without feeling hungry my weight is coming down. And I feel good!
    One last thing, for those that worry about pain, catheter etc for prostate surgery, don't. Heart bypass surgery is way more worrisome, pain, and really uncomfortable.
    Age: 65 / At surgery
    10/01/12 PSA 5.7 & climbing
    10/25/12 Transrectal biopsy / results T2 b/c Score of 3-4 & 4-3 / Gleason Score 7
    10/28/12 Consultation with Surgeon Dr. Vipul Patel (8,000+ surgeries) for Da-Vinci Radical Prostatectomy (my choice)
    01/11/13 Da-Vinci Prostatectomy, Florida Celebration Hosp. (above surgeon), Cancer confined within prostate capsule & none found in margins or lymph nodes.
    02/26/13 PSA test <.01
    06/11/13 PSA test <.01 and Testosterone 510
    09/09/13 PSA test <.01
    01/15/14 PSA test <.01
    07/21/14 PSA test <.01
    07/28/15 PSA test <.01
    02/02/16 Quadruple Bypass Heart Surgery
    06/28/16 PSA test <.01
    03/18/19 PSA tested yearly and to date still <.01

  8. #18
    Sarg, thanks for your post and I hope your recovery goes uneventfully well.

    I'm curious about the salt issue. I know that salt is a negative, I always assumed it was a blood pressure issue, and since my BP is perfect with low dose meds, I've ignored it. I LOVE salt. I put it on everything.
    So I guess my question is...did the hospital dietitian talk to you about the REASONING for restricting salt?

    PORTION Control is tough for me too, but I've gotten better. I can tell you losing weight, even just 5% of body weight, will make a world of difference.
    Diagnosed at age 64 (in November, 2014), PSA 4.3
    Nov 2014 BX 3 of 12 cores positive original pathology G8. Johns Hopkins second opinion, G6
    Surgery with Dr Ash Tewari Jan 6, 2015
    Post surgical pathology, stage T2c, bilateral disease, upstaged to G7(3+4)
    5% of Prostate involved in Tumor. Organ confined, Margins, SV, lymph nodes (9) all negative, PNI positive
    PSA <.02 until (uh-oh), 2/17 .02. Then 5/17-.033, 8/17-.033, 11/17-.046, 4/18-.060, 6/18-.068, 7/18- .082, 8/18-. 078.
    Decipher score low risk, .37
    ADT/Firmagon started August 2018. SRT to start SEPT 2018. Finished SRT November 2018, Finished ADT Feb 2019
    T=7, PSA <.05

  9. #19
    Senior User
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    Pratoman,
    From what the surgeon said my blockages in the heart were from calcium which is in the sodium category. Basically not much difference between the two from what I understand. For what it is worth my blood pressure was never high either. Took a few days to kind of loose the taste for salt, but when in the hospital there wasn't an option. Mrs. Dash makes some interesting alternatives that I have grown to like.
    So far I have lost about 12 pounds from when I went in the hospital and would like to loose about another 10.
    Age: 65 / At surgery
    10/01/12 PSA 5.7 & climbing
    10/25/12 Transrectal biopsy / results T2 b/c Score of 3-4 & 4-3 / Gleason Score 7
    10/28/12 Consultation with Surgeon Dr. Vipul Patel (8,000+ surgeries) for Da-Vinci Radical Prostatectomy (my choice)
    01/11/13 Da-Vinci Prostatectomy, Florida Celebration Hosp. (above surgeon), Cancer confined within prostate capsule & none found in margins or lymph nodes.
    02/26/13 PSA test <.01
    06/11/13 PSA test <.01 and Testosterone 510
    09/09/13 PSA test <.01
    01/15/14 PSA test <.01
    07/21/14 PSA test <.01
    07/28/15 PSA test <.01
    02/02/16 Quadruple Bypass Heart Surgery
    06/28/16 PSA test <.01
    03/18/19 PSA tested yearly and to date still <.01

  10. #20
    Administrator Top User Kermica's Avatar
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    Very interesting thread for me, thanks to everyone for your contributions. I was just told in December that I have CAD and that it was advancing at a rate of more than 50% per year. We are still assessing options but I was fortunate in that my cardiologist found this early when my CAC count went from 34 to 72 in less than two years. The numbers are still low but the rate of increase has him very concerned.

    Now, has anyone checked their GFR (glomerular filtration rate)? It is an indication of kidney function and, if the number is below 60 it is an indication of chronic kidney disease (CDK). I just found out last week that mine is in the fifties so I went back through the last three years of oncology blood test results and found that the number has been in steady decline over the past year but was fine before that.

    The reason I am bringing this up is that there is a huge connection between CDK and CAD. People with CDK tend to develop CAD which then tends to be very difficult to control. This article will provide the background for those interested: http://www.medscape.com/viewarticle/589926

    I am not trying to turn this discussion in a different direction but, since I have been hit with both these elements in the last six weeks, they are very much top of mind for me and so I thought I would bring the connection forward for those who may be unaware.

    Good health,

    kermica
    When the world says, "Give up," Hope whispers, "Try it one more time."
    ~Author Unknown

    Age 67
    Follicular lymphoma diagnosed August 08, Stage 1
    2 cycles (20 treatments each) localized radiation to tumor sites. Remission confirmed July 09
    Restaged to Stage 3 May 2010
    Recurrence confirmed May 2010 - Watch and Wait commenced - multiple scans with minimal progression.
    Cutaneous Squamous Cell Carcinoma diagnosed September 2012. Mohs surgical excision 09/2012. Successful, clean edges all around.
    Significant progression detected in PET scan - December 2012
    Biopsy to check for transformation 1/18/2013 - negative for that but full of lymphoma, of course.
    July 2013 - Rescan due to progression shows one tumor (among many) very suspect for transformation, another biopsy 8/12/13.
    August 2013 - No evidence of transformation, 6 courses of B+R commence 8/29 due to "extensive, systemic disease".
    February 2014 - Diagnostic PET scan states: Negative PET scan. Previous noted hypermetabolic cervical, axillary, iliac and inguinal lymphadenopathy has resolved. Doctor confirms full remission.
    June 2014 - started 2 year maintenance Rituxan, 1 infusion every 3 months. Doctor confirms lump under right arm are "suspicious" for recurrent disease, deferring scans for now.
    February 2015 - Doc and I agreed to stop R maintenance as it is depressing my immune system too much.
    June 2015 - Confirm that the beast is back by physical exam, will scan in August after esophageal issues settle down so we can get a clear view.
    August 2015 - physical exam in error, PET/CT shows no evidence of disease. Remission continues well into second year!
    December 2015 - Cardiologist tells me I have plaque buildup growing at an alarming rate. Stent or bypass down the road but not yet...
    March 2016 - new tumor below the jaw so remission is over. Back to active surveillance until treatment is needed.
    June 2016 - C/T scan indicates presence of multiple lesions in iliac chain.
    August 2016 - PET/CT shows multiple areas of lymphoma as expected plus new areas of concern in bowel.
    January 2017 - C/T scan shows significant progression in cervical and inguinal lymph chains, largest tumor is impacting hearing, measures 2.1x4.6 cm. 4 to 8 cycles of R-CVP, 1x3weeks to commence 2/6/17.
    April 2017 - Mid treatment scan shows about 1/3 reduction in multiple tumors. Also shows abdominal aortic aneurysm with peripheral thrombus. Cardiologist changed meds, spoke of need for surgical repair down the road.
    September 2017 - finished 10 rounds of R-CP, V was stopped due to neuropathy in feet. No further treatment planned at this time, at least 10 tumors can be felt which seem to be growing again.
    December 2017 - Biopsy of external iliac node with SUV of 13.1 shows no transformation! However, the FL grade is now 3A instead of Gr 1-2. Will start indefinite protocol using Copanlisib, one of the new targeted therapies. I remain hopeful.
    March 2018 - Copanlisib failed, treatment stopped 3/28. New plan is to go to Dana Farber on 4/16 for case review and treatment recommendation.

    May 2018 - did not qualify for clinical trials at Dana Farber. Tumors need to get larger to be considered. On consultation w/Dr. Armand at DF and my onc, have decided to take a break from cancer treatments. Will have a biopsy of the mass in my sinus discovered in scan at DF and to get the aneurysm repaired as it has developed a potentially catastrophic penetrating ulcer. Surgery scheduled for 7/12.

    September 2018 - biopsy of mass in nose shows transformed DLBCL throughout. Assessing options for this negative development.

    October 2018 - started 6 to 8 cycles of R-CHOP. Goal is to get to full remission to open up other options.

    February/March 2019 - PET shows four hot spots following R-CHOP. referred to Dana Farber for stem cell transplant. Pre testing all good, accepted for Auto Transplant. Will begin inpatient process about April 1.

 

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