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Thread: Cystine deprivation and tripple negative breast cancer

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    Cystine deprivation and triple negative breast cancer


    In a new study, Duke University scientists report that cells from a vicious and treatment-resistant form of breast cancer, called triple negative breast cancer (TNBC), die off rapidly when deprived of a key nutrient called cystine. By examining the cause of cell death, they found that this "cystine addiction" is triggered by a mechanism that many kinds of tumor cells use to break away and migrate to new locations in the body.

    The results indicate that blocking cystine uptake may be an effective way of treating not only triple negative breast cancer, but other aggressive cancers that use this pathway during metastasis. The study appeared online Nov. 21 in Oncogene.
    Last edited by lancepeace; 11-26-2016 at 01:22 PM.


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