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Thread: My wife passed away last night.

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  1. #1
    Senior User
    Join Date
    Nov 2009
    Location
    Louisiana
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    My wife passed away last night.

    Her death was painless. She died peacefully. Just stopped breathing.

    Thanks forum members for your support.
    My wife was diagnosed with grade II Oligodendroglioma in November, 2009 at age 49. Started Temodar in January 2010. Stopped Temodar June 2011. Recurrence confirmed July 2013. Temodar again from April 2014 to March 2015. Recurrence in April 2015. Radiation May-June 2015. Recurrence January 2016. Tumor is bi-lateral and multi-focal.

    Partial resection in Feb. 2016. Confirmed progression to oligo 3.

    May 2016 diagnosed with breast cancer. Lumpectomy June 2016. No further treatment recommended for breast cancer, due to priority of brain cancer treatment.

    Emergency resection July 2016. Started dex.

    Started Avastin August 2016.

  2. #2
    Super Moderator Top User po18guy's Avatar
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    Feb 2012
    Location
    Pacific NW, USA
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    6,746
    I can only imagine the heartache. All I can offer is a simple prayer.

    Eternal rest grant unto her and let perpetual light shine upon her. May her loved ones receive consolation in this time of sorrow.
    07/08 Age 56 DX 1) Peripheral T-Cell Lymphoma-Not Otherwise Specified. 50+ tumors with BMI
    08/08-12/08 Four cycles CHOEP14 + four cycles GND (Cyclofosfamide, Doxorubicin, Vincristine, Etoposide, Prednisone & Gemcitabine, Navelbine, Doxil)
    02/09 2) Relapse.
    03/09-06/13 Clinical trial of Romidepsin > long-term study. NED for 64 twenty-eight day cycles
    07/13 3) Relapse, 4) Suspected Mutation.
    08/13-02/14 Romidepsin increased, but stopped due to ineffectiveness. Watch & Wait.
    09/14 Relapse/Progression. Visible cervical nodes appear within 4 days of being checked clear.
    10/06/14 One cycle Belinostat. Discontinued to enter second clinical trial.
    10/25/14 Clinical trial of Alisertib/Failed.
    01/12/15 Belinostat resumed/Failed 02/23/15
    02/24/15 Pralatrexate/Failed 04/17/15
    04/15 Genomic profiling reveals mutation into PTCL-NOS + AngioImmunoblastic T-Cell Lymphoma. Two dozen tumors + small intestine (Ileum) involvement.
    04/22/15 TREC (Bendamustine, Etoposide, Carboplatin). Full response in two cycles. PET/CT both clear. Third cycle followed.
    06/15-07/15 Transplant preparation (X-rays, spinal taps, BMB, blood test, MUGA scan, lung function, CMV screening, C-Diff testing etc. etc. etc.) Intrathecal Methotrexate during spinal tap.
    BMB reveals 5) Myelodysplastic Syndrome (MDS), a type of bone marrow cancer.
    07/11-12/15 Cyclofosfamide + Fludarabine conditioning regimen.
    07/16/15 Total Body Irradiation.
    07/17/15 Haploidentical Allogeneic Transplant receiving my son's peripheral blood stem cells.
    07/21-22/15 Triple dose Cyclofosfamide + Mesna, followed by immunosuppressants Tacrolimus and Mycophenolate Mofetil.
    07/23-08/03/15 Blood nose dive. Fever. Hospitalized two weeks.
    08/04/15 Engraftment official - released from hospital.
    08/13/15 Marrow is 100% donor cells. Platelets climbing steadily, red cells follow.
    09/21/15 Acute skin GvHD arrives. DEXA scan reveals Osteoporosis.
    09/26/-11/03/15 Prednisone to control GvHD.
    05/2016 Tacrolimus stopped. Prednisone from 30-90mg daily tried. Sirolimus begun.
    09/16/16 Three skin punch biopsies.
    11/04/16 GvHD clinical trial of Ofatumumab (Arzerra) + Prednisone + Methylprednisolone begun.
    To date: 18 chemotherapeutic drugs in 9 regimens (4 of those drugs at least twice), + 4 immunosuppressant drugs.

    I have been chosen to suffer, therefore, I am blessed. Knowing the redemptive value of suffering makes all the difference.

    "What is faith? It is that which gives substance to our hopes, which convinces us of things we cannot see"
    - Hebrews 11:1

  3. #3
    I'm sorry for your loss

  4. #4
    Super Moderator Top User
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    Dec 2011
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    USA
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    Oh no. I'm so sorry for your loss.

  5. #5
    Experienced User
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    Apr 2013
    Location
    Georgia USA
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    My sincere sympathies to you and your family.

  6. #6
    Administrator Top User Kermica's Avatar
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    New York
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    So sorry to learn of your loss, JE. Be comforted in the knowledge that she went peacefully and without pain at the end. Sending prayers and healing thoughts.

  7. #7
    Top User mccindy's Avatar
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    Jun 2013
    Location
    Eau Claire, WI
    Posts
    607
    I'm so sorry you lost her.
    grand mal seizure leading to MRI discovery of a suspicious brain mass in left temporal lobe May 24, 2013
    99% resection of a WHO Grade II diffuse fibrillary astrocytoma July 11, 2013
    1st postoperative MRI October 11, 2013 - clear for any regrowth
    Clear MRI April 2015
    Next MRI Oct 2015
    200 mg of Topamax daily

  8. #8
    Moderator Top User
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    May 2011
    Location
    Illinois
    Posts
    764
    May her memory be eternal...
    Nikos

    Glioblastoma IV, frontal lobe - Dx March 2011. Treated with standard Stupp protocol
    Recurrence August 2016 (at 5 years PFS). Surgery August 2016, rechallenge with TMZ with immunotheraphy (nivolumab)

  9. #9
    Top User David52's Avatar
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    Jan 2013
    Location
    Central Wyoming
    Posts
    782
    Am so very sorry, je. Breaks my heart.
    64 yrs old
    March 6, 2012: Diagnosed Anaplastic Large (T-) Cell Lymphoma, Stage 1 (ALK-)
    3 rounds of CHOP unsuccessful.
    Beginning mid-June, 2012, received 6 cycles of Brentuximab at Huntsman Cancer Institute, University of Utah. Pet scans after 4th and 6th cycles showed no evidence of lymphoma.
    Autologous bone marrow transplant in November of 2012.
    17 radiation treatments for "consolidation" purposes between Dec. 26 and Jan.17.
    100 day post BMT check-up (2/26/13): NED. Pet scan on 7/10/13: Still NED.
    One year post transplant check-up: Still fine; NED.
    18month post-translant scans, etc. All fine, save a bit of arthritis.
    11/14/14: 24 month post transplant check-up--still NED. Scanziety still sucks.
    5/15/15: No NED this time; reactive nodes in groin; scheduling biopsy.
    Relapse confirmed/ started every 3 week brentuximab
    Allo transplant in Feb 2016.
    100 day post transplant scans in June 2016 fine.

  10. #10
    Experienced User Dhailstone1's Avatar
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    Apr 2015
    Location
    Ohio
    Posts
    98
    My condolences.
    Diagnosis - Oligodendroglioma II
    Seizure on 3.6.15
    Surgery on 3.10.15
    Awake Surgery at Duke Medical on 7.18.15

 

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