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Thread: Prostate adenocarcinoma and stones

  1. #1
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    Prostate adenocarcinoma and stones

    Had PSA test done on annual physical, 8.7 re-tested down to 7.0.(no sex for three days)
    Needle Biopsy 11/03 Gleason Score,
    Primary pattern G3
    Secondary (worst Remaining) G4
    total G Score 3+4=7
    Tumor Quantitation: # cores positive 5 total core 12
    % tissue involved by tumor 5%
    Tested 2013 PSA 3.54 reference range <3.5 watched(but not really)
    Age 64
    Was bummed, Doc saw prostate stones durning biopsy thought that might be reason for high PSA.
    See Doc 11/15 for follow up.
    Have seen articles that talk about prostate stones that might be cause or contribute to prostate cancer. Have not seen articles talking about treatment of prostates that are cancerous plus have stones, anybody have the same issue?

  2. #2
    Moderator Top User HighlanderCFH's Avatar
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    Welcome aboard, MEB.

    I have to admit that I'm not real familiar with prostate stones. But, aside from that, you have a moderately aggressive case of prostate cancer.

    The large number of positive cores generally disqualifies a patient from active surveillance -- which means that a treatment option should be made.

    You should consult with a top notch urologist about the good & bad associated with surgery. Then do the same thing with a top radiation oncologist who specializes in prostate cancer.

    Then you can decide on what treatment option seems best for you.

    Stay tuned to this channel -- you get lots of help from your new friends in here.

    P.S. I moved your post into the Prostate Cancer Forum so it will get the most attention.

    Good luck!
    Chuck
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections 5 years post-op whenever the moon turns into blue cheese.
    NOTE: ED caused by BPH, not the surgery.

  3. #3
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    Thanks Chuck, ultrasound during needle biopsy showed calcium build up. I'm sure CT is next.
    DOB 8/53 Age 64

    Path Report; 49 grams-5x4.5x2.5 3+4=7 group 2 40% involved.
    Margins: Adenocarcinoma less than 1 mm left side will watch close with PSA test.
    Nervers spared both side.
    7 lymph nodes tested negative for malignancy
    Perineurial invasion: present
    pathologic Stage Class (pTNM): pT2 pNO
    August 9, 2018 for Robotic Surgery
    3/5/2018 PSA 6.8 Watching, plan on Robotic Surgery August 2018 Banner M.D.Anderson cancer center. Gilbert AZ.
    12/20/17 MRI
    11/3/17 Needle Biopsy Dr. Joseph Mashni
    Primary (Predominant) Pattern G3
    Secondary (worst remaining) G4
    Total 3+4=7
    Grade Group 2
    Tumor Quantitation number of cores positive 5 total cores 14
    Percentage of prostatic tissue involved by tumor 5%
    % positive cores 35.71%
    T Stage T1C

    PSA 6/13/ 3.54 range <3.5 watch
    PSA 10/17 8.6
    PSA 10/25/17 7.0
    PSA 2/28/16 6.8
    PSA 3/28/2017 8.65
    PSA 10/17/18 0.010 2 months after Robotic Surgery

  4. #4
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    The prostate stones are of interest to me. My CT scan showed dense calcification in my prostate. Could this make your PSA higher than normal?
    My PSA is now 8.7.
    My biopsy showed 2 cores positive for cancer and one suspicious. I am doing AS but as of today my urologist wants another biopsy. I had the original biopsy in February of his year (2017).
    I wondered about the prostate stones but did not ask my doctor.

  5. #5
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    I am seeing my urologist tomorrow, I am going to ask about the stones, I am sure he wants a CT will know more after that.
    What I have read there is a likely hood of cancer when here are stones present.
    DOB 8/53 Age 64

    Path Report; 49 grams-5x4.5x2.5 3+4=7 group 2 40% involved.
    Margins: Adenocarcinoma less than 1 mm left side will watch close with PSA test.
    Nervers spared both side.
    7 lymph nodes tested negative for malignancy
    Perineurial invasion: present
    pathologic Stage Class (pTNM): pT2 pNO
    August 9, 2018 for Robotic Surgery
    3/5/2018 PSA 6.8 Watching, plan on Robotic Surgery August 2018 Banner M.D.Anderson cancer center. Gilbert AZ.
    12/20/17 MRI
    11/3/17 Needle Biopsy Dr. Joseph Mashni
    Primary (Predominant) Pattern G3
    Secondary (worst remaining) G4
    Total 3+4=7
    Grade Group 2
    Tumor Quantitation number of cores positive 5 total cores 14
    Percentage of prostatic tissue involved by tumor 5%
    % positive cores 35.71%
    T Stage T1C

    PSA 6/13/ 3.54 range <3.5 watch
    PSA 10/17 8.6
    PSA 10/25/17 7.0
    PSA 2/28/16 6.8
    PSA 3/28/2017 8.65
    PSA 10/17/18 0.010 2 months after Robotic Surgery

  6. #6
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    I will check back to see what you find out. I have had the dense calcification in my prostate for several years, long before I started this horrible prostate journey. Best of luck.

  7. #7
    Moderator Top User HighlanderCFH's Avatar
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    Good luck, MEB.

    Same for you, Darius.
    July 2011 local PSA lab reading 6.41 (from 4.1 in 2009). Mayo Clinic PSA 9/ 2011 = 5.7.
    Local uro DRE revealed significant BPH, no lumps.
    PCa Dx Aug. 2011 age of 61.
    Biopsy DXd adenocarcinoma in 3/20 cores (one 5%, two 20%). T2C.
    Gleason 3+3=6. CT abdomen, bone scan negative.
    DaVinci prostatectomy 11/1/11 at Mayo Clinic (Rochester, MN), nerve sparing, age 62.
    Surgeon was Dr. Matthew Tollefson, who I highly recommend.
    Final pathology shows tumor confined to prostate.
    5 lymph nodes, seminal vesicules, extraprostatic soft tissue all negative.
    1.0 x 0.6 x 0.6 cm mass involving right posterior inferior, right posterior apex & left
    mid posterior prostate. Right posterior apex margin involved by tumor over 0.2 cm length,
    doctor says this is insignificant.
    Prostate 98 grams, tumor 2 grams.
    Catheter out in 7 days. No incontinence, minor dripping for a few weeks.
    Seven annual post-op exams 2012 through 2018: PSA <0.1
    Semi-firm erections 5 years post-op whenever the moon turns into blue cheese.
    NOTE: ED caused by BPH, not the surgery.

  8. #8
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    11\15 Saw oncologist today, I asked him about the stones and he showed me in my pathology report that most of my cores showed chronic inflammation, which is the Calcification. Calcification which is a foreign body in the prostate will cause the inflammation and can raise your PSA.
    The jury is still out whether or not calcification is a cause or factor for prostate cancer.
    At this time I have no issue with my prostate other than slow stream, no pain.
    Doc ordered MRI 12/20, give time for prostate to heal from biopsy (by the way biopsy was painless except for the two antibiotic shot in the cheeks pre-test)
    Will meet with radiologist same day of MRI and surgeon the next week and go over options. In the mean time I will be researching all the different options.
    Also asked that the Doctor send my lab off for genetic testing.
    Going to enjoy the Holiday.
    DOB 8/53 Age 64

    Path Report; 49 grams-5x4.5x2.5 3+4=7 group 2 40% involved.
    Margins: Adenocarcinoma less than 1 mm left side will watch close with PSA test.
    Nervers spared both side.
    7 lymph nodes tested negative for malignancy
    Perineurial invasion: present
    pathologic Stage Class (pTNM): pT2 pNO
    August 9, 2018 for Robotic Surgery
    3/5/2018 PSA 6.8 Watching, plan on Robotic Surgery August 2018 Banner M.D.Anderson cancer center. Gilbert AZ.
    12/20/17 MRI
    11/3/17 Needle Biopsy Dr. Joseph Mashni
    Primary (Predominant) Pattern G3
    Secondary (worst remaining) G4
    Total 3+4=7
    Grade Group 2
    Tumor Quantitation number of cores positive 5 total cores 14
    Percentage of prostatic tissue involved by tumor 5%
    % positive cores 35.71%
    T Stage T1C

    PSA 6/13/ 3.54 range <3.5 watch
    PSA 10/17 8.6
    PSA 10/25/17 7.0
    PSA 2/28/16 6.8
    PSA 3/28/2017 8.65
    PSA 10/17/18 0.010 2 months after Robotic Surgery

  9. #9
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    Thanks Highlander and thanks for posting the calcification info 1953MEB. That is encouraging to me. Hoping that the dense calcifications in my prostate could be part of the rise in my PSA and not an indicator if spreading cancer. Totally went blank at the doctors office today and forgot to ask about the calcification. My wife went with me and she forgot too.
    My prostate is really acting up now...severe pain this morning and constant but not as severe pain right now. My urologist previously told me that cancer is not the cause of those symptoms so I'm thinking I have an infection or maybe just a flare up.
    If my next PSA is high again.....I will have the biopsy and my doctor talked about radiation as opposed to surgery....if needed at all.
    This site is a great source of information and I'm so grateful I can read the information here.

    Dense calcification in otherwise unremarkable CT scan in December of 2016
    12 core biopsy in February 2017
    2 cores positive, both 3+3=6 (one 50% and one 5%)
    1 core suspicious
    PSA Oct 2016 = 6.23
    PSA Nov 2016 = 5.9
    PSA April 2017 = 7.2
    PSA July 2017 = ?
    PSA September 2017 = 6.8
    PSA Nov 2017 = 8.7 (Having urinary symptoms)

  10. #10
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    Starting to do my research, (a little late) and putting together questions for my next visit, one question is, MRI is it a DCE-MRI or just an MRI, its scheduled for 12-20. Have done a lot of reading on DCE-MRI its newer and not all cancer centers have it in use, but the upside to using DCE-MRI is pin pointing cancer cells.
    Did ask for a genetic testing to be done on the blind biopsy.
    Its to late to ask the doctor now but I would like to see what he has to say about why in 2017 are we still doing blind testing biopsy and not using DCE-MRI first to pinpoint where "if" any cancer is. Would seem better to do 4-5 pin point needle test than 14 blind test and hope you got lucky and found all the cancer.
    There maybe a really good reason it's done this way, but to me it seem backwards.
    If anyone out there who is getting ready to see the Doctor because of high PSA score ask that question. If anyone on this forum has already asked this question, or done pin point biopsy might be helpful to guys just getting started with the process.
    Having 3+4 reading takes me out of the low risk treatments, so need to focus on what type of long term treatment I need.
    For guys just getting started with this process ASK LOTS OF QUESTIONS, do lots of research there is tons of info out there on the net, and in excellent forums like this one. Take someone into the Doc room with you trust me your mind will only catch and retain 5% of what is being said, thanks to my wife she was able to ask all the right question because I went blank. Write down your questions
    ahead of time, If your Doc gets pissy about answering your question find another doctor.
    More research, you have time. and good luck. check out link Prostatecaluater.net.
    Will update after 12/20. MRI and visit with Oncologist, radiologist
    DOB 8/53 Age 64

    Path Report; 49 grams-5x4.5x2.5 3+4=7 group 2 40% involved.
    Margins: Adenocarcinoma less than 1 mm left side will watch close with PSA test.
    Nervers spared both side.
    7 lymph nodes tested negative for malignancy
    Perineurial invasion: present
    pathologic Stage Class (pTNM): pT2 pNO
    August 9, 2018 for Robotic Surgery
    3/5/2018 PSA 6.8 Watching, plan on Robotic Surgery August 2018 Banner M.D.Anderson cancer center. Gilbert AZ.
    12/20/17 MRI
    11/3/17 Needle Biopsy Dr. Joseph Mashni
    Primary (Predominant) Pattern G3
    Secondary (worst remaining) G4
    Total 3+4=7
    Grade Group 2
    Tumor Quantitation number of cores positive 5 total cores 14
    Percentage of prostatic tissue involved by tumor 5%
    % positive cores 35.71%
    T Stage T1C

    PSA 6/13/ 3.54 range <3.5 watch
    PSA 10/17 8.6
    PSA 10/25/17 7.0
    PSA 2/28/16 6.8
    PSA 3/28/2017 8.65
    PSA 10/17/18 0.010 2 months after Robotic Surgery

 

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