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Thread: Excisional biopsy

  1. #11
    I just had an excisional biopsy on a similar sized mass in my neck a week ago. The incision is about an inch long and they used surgical glue instead of stitches. The only pain I experienced was a scratchy throat from the general anesthesia and neck pain when I lifted my neck getting in and out of bed. The pain only lasted about two days and it's just felt stiff and irritated after but not painful.

    I hope you get good results and that your surgery goes well. My doctors thought the mass was a necrotic node but it turned out to be an eptopic thyroid tissue and was benign.

    I would call and ask the doctor about any concerns regarding your sore throat, but I don't think it should be an issue. It doesn't hurt to ask!
    Robyn, 23 F
    6.30.2017 Colonoscopy after a Crohn's flare, a few "normal looking" polyps found.
    7.24.2017 Doctor calls about results month later with two different Pathology reports positive for DLBCL.
    8.23.2017 Final diagnosis as (PTLD) DLBCL Stage 1EA

  2. #12
    Newbie New User dbz's Avatar
    Join Date
    Dec 2017
    Hi Brodie,

    They don't remove all the swollen lymph nodes. In my case I had deeper ones, and on the left side of my neck too, they just remove enough tissue to analyse (pathology/IHC), so the superficial lymph nodes do the job. I had a huge bulge superficially, hence they removed it all to have adequate tissue, but let the deeper swollen nodes remain. So, don't worry about it at all. And about your sickness, don't worry, its common. Since you have a swelling in your neck, you might have slight difficulty in breathing, sore throat, and yeah sore throat leads to you losing your voice. All these don't matter for the biopsy, its just a simple surgery. Hope it goes well for you and do not think much about it, its really a painless procedure.

  3. #13
    Just wanted to update everyone! I was supposed to have the excisional biopsy on 12/18 but I ended up with strep so they pushed it back to 1/3/18. Getting nervous! Will update with results. Fingers crossed

  4. #14
    Super Moderator Top User po18guy's Avatar
    Join Date
    Feb 2012
    You will do just fine. Walk in. Walk out.
    05/08-07/08 Tumor appears behind left ear. Followed by serial medical incompetence on the parts of PCP, veteran oncologist and pathologist (misdiagnosis via non-diagnosis). Providential guidance to proper care at an NCI designated comprehensive cancer center.
    07/08 Age 56 DX 1) Peripheral T-Cell Lymphoma-Not Otherwise Specified. Stage IV-B, >50 ("innumerable") tumors, bone marrow involvement.
    08/08-12/08 Four cycles CHOEP14 + four cycles GND (Cyclofosfamide, Doxorubicin, Vincristine, Etoposide, Prednisone & Gemcitabine, Navelbine, Doxil)
    02/09 2) Relapse.
    03/09-06/13 Clinical trial of Romidepsin > long-term study. NED for 64 twenty-eight day cycles, dose tapered.
    07/13 3) Relapse, 4) Suspected Mutation.
    08/13-02/14 Romidepsin increased, stopped for lack of response. Watch & Wait.
    09/14 Relapse/Progression. Visible cervical nodes appear within 4 days of being checked clear.
    10/06/14 One cycle Belinostat. Discontinued to enter second clinical trial.
    10/25/14 Clinical trial of Alisertib/Failed - Progression.
    01/12/15 Belinostat resumed/Failed - Progression. 02/23/15
    02/24/15 Pralatrexate/Failed - Progression. 04/17/15
    04/15 Genomic profiling reveals mutation into PTCL-NOS + AngioImmunoblastic T-Cell Lymphoma. Stage IV-B a second time. Two dozen tumors + small intestine (Ileum) involvement.
    04/22/15 TEC (Bendamustine, Etoposide, Carboplatin). Full response in two cycles. PET/CT both clear. Third cycle followed.
    06/15-07/15 Transplant preparation (X-rays, spinal taps, BMB, blood test, MUGA scan, lung function, CMV screening, C-Diff testing etc. etc. etc.) Intrathecal Methotrexate during spinal tap.
    BMB reveals 5) 26% blast cells of 20q Deletion Myelodysplastic Syndrome MDS), a bone marrow cancer and precursor to Acute Myeloid Leukemia.
    07/11-12/15 Cyclofosfamide + Fludarabine conditioning regimen.
    07/16/15 Total Body Irradiation.
    07/17/15 Moderate intensity Haploidentical Allogeneic Stem Cell Transplant receiving my son's peripheral blood stem cells.
    07/21-22/15 Triple dose Cyclofosfamide + Mesna, followed by immunosuppressants Tacrolimus and Mycophenolate Mofetil.
    07/23-08/03/15 Marrow producing zero blood cells. Fever. Hospitalized two weeks.
    08/04/15 Engraftment occurs, and blood cells are measurable - released from hospital.
    08/13/15 Day 26 - Marrow is 100% donor cells. Platelets climbing steadily, red cells follow.
    09/21/15 Acute skin Graft versus Host Disease arrives.
    DEXA scan reveals Osteoporosis.
    09/26/-11/03/15 Prednisone to control skin GvHD.
    11/2015 Acute GvHD re-classified to Chronic Graft versus Host Disease.
    05/2016 Tacrolimus stopped. Prednisone from 30-90mg daily tried. Sirolimus begun. Narrow-band UV-B therapy started, but discontinued for lack of response. One treatment of P-UVAreceived, but halted due to medication reaction.
    09/16/16 Three skin punch biopsies.
    11/04/16 GvHD clinical trial of Ofatumumab (Arzerra) + Prednisone + Methylprednisolone begun.
    12/16 Type II Diabetes, Hypertension - both treatment-related.
    05/17 Extracorporeal Photopheresis (ECP) begun in attempt to control chronic Graft-versus-Host-Disease (cGvHD. 8 year old Power Port removed and replaced with Vortex (Smart) Port for ECP.
    05/2017 Chronic anemia (low hematocrit). Chronic kidney disease. Cataracts from radiation and steroids.
    06/17 Trying various antibiotics in a search for tolerable prophylaxis.
    08/17 Bone marrow biopsy reveals the presence of 2% cells with 20q Deletion Myelodysplastic Syndrome, considered to be Minimum Residual Disease.
    12/17 Bone marrow biopsy reveals no abnormalities in the marrow - MDS eradicated. The steroid taper continues.
    01/18 Consented for Kadmon clinical trial.
    03/18 Began 400mg daily of KD025, a rho-Associated Coiled-coil Kinase 2 Inhibitor (ROCK2).
    09/18 Due to refractory GvHD, Extracorporeal Photopheresis halted after 15 months ue to lack of additional benefit.
    10/18 I was withdrawn from the Kadmon KD025 clinical trial due to increasing fatigue/lack of benefit.
    11/18 Began therapy with Ruxolitinib (Jakafi), a JAK 1&2 inhibitor class drug. Started at half-dose due to concerns with drug interactions.

    To date: 1 cancer, relapse, second relapse/mutation into 2 cancers, then 3 cancers simultaneously, 20 chemotherapy/GVHD drugs in 11 regimens (4 of them at least twice), 5 salvage regimens, 4 clinical trials, 5 post-transplant immuno-suppressant/modulatory drugs, the equivalent of 1,000 years of background radiation from 40+ CT series scans and about 24 PET scans.
    Both lymphoid and myeloid malignancies lend a certain symmetry to the hematological journey.

    Believing in the redemptive value of suffering makes all the difference.

  5. #15
    Just got home from the surgery even though it was supposed to start at 9 am they were 3 hours behind! If you are a naturally nervous person like me it sucks, but for a normal person it would be fine! Waking up was a little tough with severe dizziness and nausea but other than that everything went as planned and I should have my results in a week! Scar is quite big though wasn’t expecting that.

  6. #16
    Super Moderator Top User
    Join Date
    Dec 2011
    Scars just show we've been around. Hope the biopsy comes back negative.

  7. #17
    Just wanted to update with my results:
    Reactive follicular and parafollicular lymphoid hyperplasia

  8. #18
    Super Moderator Top User
    Join Date
    Dec 2011
    Good news!

  9. #19
    Moderator Senior User IndyLou's Avatar
    Join Date
    Jan 2014
    That's great news, Brodie. We're all glad for you. I hope you heal nicely, and have a healthy and happy year!
    Age 52 Male
    early Feb, 2013 - Noticed almond-sized lump in shaving area, right side of neck. No other "classic" cancer symptoms
    late Feb, 2013 - Visited PCP for check-up, PCP advised as lymphoma. Did blood work, orders for CT-scan, referred to ENT
    3/7/13 - CT-scan inconclusive, endoscopy negative
    3/9/13 - FNA of neck mass
    3/14/13 - Received dx of squamous-cell carcinoma, unknown primary
    3/25/13 - CT-PET scan reveals no other active tumors
    3/26/13 - work/up for IMRT
    4/1/13 - W1, D1 of weekly cetuximab
    4/8/13 - W1, D1 of IMRT
    5/20/13 - complete 8 week regimen of weekly cetuximab
    5/24/13 - Complete 35-day regimen of daily IMRT
    mid-July 2013 - CT-PET scan reveals no active tumors, but shows necrotic tissue at site of original tumor
    early Sept 2013 - partial neck dissection to remove necrotic tissue. Assay shows no cancer present.
    Spring 2014 - No signs of cancer
    Spring 2015 - NED
    Spring 2016 - NED
    Spring 2017 - NED
    Spring 2018 - NED

  10. #20
    Thanks guys! Quick question- even though my results came back reactive, why are they doing clonality testing? Those results are not back yet? I saw something like T cell, B cell, and EBV? Not sure what any of that means. Any insight would be helpful, thanks!


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