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Thread: Recent Diet News For Us Guys

  1. #1

    Recent Diet News For Us Guys

    Mediterranean dietary pattern and the risk of prostate cancer. A meta-analysis [2019, Full Text]

    Conclusion
    This large meta-analysis of observational studies suggests that Mediterranean dietary pattern has no relationship with prostate cancer risk .

    Dynamic metabolic response of prostate cancer patients treated with ADT and low carb diet [2019]

    Background: Prostate cancer (PrCa) is one of the most common cancers among men and managed through surgery, hormonal therapy, chemotherapy, radiation, and cryotherapy. Depending on the stage of PrCa, androgen deprivation therapy (ADT) is commonly utilized as an intervention. ADT has proven effective in intervening in PrCa progression, although there are several side effects. Recently, the use of low carb diets has been shown to alter patients’ metabolic phenotype* and as such may reduce the side effects of ADT.

    Vegetables: to Cook or Not to Cook [2019, Article]

    ...
    Nutritionally, there are pluses and minuses to cooking vegetables,” says Helen Rasmussen, PhD, RD, a senior research dietitian at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. For example, cooking carrots reduces levels of vitamin C (which plays an important role in maintaining collagen, the glue that holds cells together) but increases availability of beta-carotene, a precursor of vitamin A (which plays an important role in vision, reproduction, bone growth, and regulating the immune system).
    ...
    I remember that cooked/processed tomatoes have more lycopene than raw. However:
    Dietary Tomato, but Not Lycopene Supplementation, Impacts Molecular Outcomes of Castration-resistant Prostate Cancer in the TRAMP** Model [2019]


    Vitamin K2 prevents prostate cancer, cardiovascular disease, and bone weakness [2019, Article]

    Can Vitamin K2 be used as a potential therapy for prostate cancer?
    To answer the question, a group of scientists from the University of Illinois analyzed both the results of their own research and available literature data. According to their review, vitamin K inhibits the growth of cancer cells through apoptosis, cell cycle arrest, and autophagy and can potentially be explored as a therapy for prostate cancer. Apoptosis is a programmed cell death that takes place during normal organisms development.
    ...
    Conclusion
    Since nor any form of vitamin K has yet been tested for mutagenicity, it is advisable to use natural food sources of vitamin K. The most accessible sources of vitamin K2 are eggs, dairy foods of fermentation, cheese, curd, sauerkraut, liver, and natto. Natto would definitely be the best choice, but for some reason, it is not so popular on the American or European markets yet, and therefore the price is pretty high. If using animal products, remember, they must be from pastured cows or chickens.
    If these foods are inaccessible to you, taking supplements is a proven alternative. Moreover, you can find some excellent combinations of vitamin K2 and vitamin D3 on Amazon. Vitamin D3 is another natural food component the anticancer properties of which has been proven scientifically.

    Take care of your health, be aware before you put anything inside your body.
    (All emphasis mine)

    Logically speaking, the bigger the dietary claim, the more salt you should take it with (good one, no??). In vivo, but non-human, positive results are only a starting point, although a very good one that is a step above in vitro results. Often we can't get equivalent bioavailability in humans without dosages that are too risky/toxic.
    _______________
    * This is, I believe, the mechanism that explains, for example, why folks who are lactose intolerant are not necessarily so continuously, but sometimes go through even long periods in which they are or aren't. A gene is probably getting switched on or off by environmental factors/diet. Your genotype (genes) obviously remains the same, but your phenoype (gene expression) changes. In this example your ability to make the enzyme lactase.

    **TRAMP mice are those with no fixed abode and no demonstrable source of income. "TRAMP stands for TRansgenic Adenocarcinoma Mouse Prostate. Lines 5666 and 8079 were also produced. Transgenic mice on a C57BL6 background develop progressive forms of prostate cancer with distant site metastasis."
    Last edited by DjinTonic; 07-12-2019 at 10:32 AM.

  2. #2
    Thanks for the post. These things always interest me and while they might or might not help, they are risk-free things we can do on top of whatever the medical community has to offer.
    Last edited by Hawk; 07-11-2019 at 03:39 PM.
    History: age 53 It took 3 biopsies (34 cores) to find 2 cores 4+4 Gleason 8
    Lap RP at MSKCC Apr 2004, age 54 All neg margins, nodes & structures. (T2a).
    Post RP PSA: <.1 until Feb, 08 (46 mos) PSA 0.1 - I then got sensitive tests -> 2008: Feb 0.06,
    May-08 0.09 - Jun-08 0.10, - Aug-08 0.10, - Nov-08 0.15
    SRT Dec-2008 ---Post SRT PSA 2009, Feb-09 0.10, May-09 0.09, Aug-09 0.06, Dec-09 .04, - 2010 Mar-09 0.04, 2011 .02, 2012 .02,
    STARTED UP Feb 2014-0.06, Jul-2015 0.10, Oct-2015 0.10, Feb-2016 0.15, Jun-2016 0.17, Dec-2016 0.25, Jan-2019 0.74, Jun -2019 0.72
    Aug 2018 Auximin scan - nothing
    Had an inflatable penile implant 2018 for ED. Best decision ever https://www.peyroniesforum.net/index...oard,56.0.html

  3. #3
    Quote Originally Posted by Hawk View Post
    Thanks for the post. These things always interest me and while the might or might not help, they are risk-free things we can do on top of whatever the medical community has to offer.
    You're very welcome. See also Topic (S) in our Subforum near the top of the main page. It links dozens of studies on phytochemicals and diet.

    Djin

  4. #4
    Top User
    Join Date
    Aug 2016
    Posts
    1,653
    I have a buddy who swears by a variation of the Mediterranean diet. I suspect he has prostate cancer and he admits he probably does and this, among other things, is his "treatment" for it. I do not discuss my situation with him after doing so once. He doesn't want to hear it. He's a casualty of the initial negative biopsy syndrome.
    Born 1953
    family w/PCa; grandfather, 3 brothers
    07-12-04 PSA 1.90
    07-10-06 PSA 2.02
    08-30-07 PSA 3.20
    12-01-11 PSA 5.69 Internist recommends urologist, I say no
    05-16-12 PSA 4.76 manipulate w/diet & supplements
    12-11-12 PSA 5.20, Health system changes to 3 years on testing
    03-07-16 PSA 7.20 Internist adamant on urologist
    DRE smooth, enlarged
    03-14-16 TRUS biopsy-prostatic adenocarcinoma 1%-60% across 8 of 12 samples, Gleason 3+3=6
    03-31-16 MRI pelvis w/o dye
    05-04-16 DaVinci prostatectomy, nerve sparing, Dr. Kent Adkins - recommend
    Final Path; weight 65g, lymph nodes, seminal vesicles, capsule, margin all negative, Gleason 3+4=7, Tumor volume 35%, +pT2c
    Catheter out - 16 days
    Incontinence at 6mos is minimal – no pad
    Cialis 3x/wk & Viagra on occasion
    Begin self-injection needle therapy for erections, stop after 6 due to onset of Peyronie’s
    Erections 100% - 14 months
    5-21-19 PSA <0.02, Zero Club 3.5 years

 

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