A website to provide support for people who have or have had any type of cancer, for their caregivers and for their family members.
Results 1 to 9 of 9

Thread: Continuing Membership in the "Zero Club"

  1. #1
    Senior User
    Join Date
    Feb 2017
    Posts
    178

    Continuing Membership in the "Zero Club"

    My exit from the two year clinical trial is now complete. Blood drawn at 8 am. CBC, Testosterone, and PSA.. Results were in by this afternoon. The mild anemia has been resolved (after effects from chemo), the testosterone is still suppressed, and PSA remains undetectable. (THAT is the best news!) I am also disenrolled from additional ADT.

    The "undetectable" renews my membership in the Zero PSA Club.

    My doctor wants to continue seeing me every 90 days for the next two years. I will also continue having bone scans and MRI's every 6 months. His words, "if something runs amiss I want to know sooner than later so we can initiate treatment."

    I will be able to have the nuclear medicine appointments done in Greensboro.

    One advantage of having a PSA done at Hopkins is "same day results." THAT is good for my psyche!
    2010-PSA 3.59; 2011-PSA 3.58; 2012-PSA 5.28, 4.26; 2013-PSA 5.98, 7.37; 2014-PSA 5.90, 4.70; 2015-PSA 5.18, 7.35
    RALP 16 March 17, Wesley Long, Greensboro, NC
    Pathology: pT3a, pN1 Gleason 4+5=9 adenocarcinoma with + surgical margin at bladder neck; 3 of 16 lymph nodes positive; neg seminal vesicles, vasa deferens
    Referral to Dr. Ken Pienta, Clinical Dir Research, Brady Center, Johns Hopkins
    Enrolled in Clinical Trial IRB002120414 “Phase II Study of definitive therapy for oligometastatic prostate cancer post surgery"
    Completed: Docetaxel 12 Jun 17, 3 Jul 17, 24 Jul 17, 14 Aug 17, 15 Sep 17
    Lupron every 90 days for two years. Completed March 2019
    Bone/Body Scans - 15 Sep 17 - neg; 15 Mar 18 - neg; 14 Sep 18 - neg; 17 Mar 19 - neg
    EBRT: 69 Gy total (46 to fossa, 23 boost to suspect areas) 1st treatment 28 Sep 17, last 22 Nov 17
    PSA: 25 May 17=0.2; 5 Sep 17=0.1; 18 Dec 17=0.1; 6 Mar 18=0.1; 29 May 18=0.1; 5 Sep 18=0.1; 17 Dec 18=0.1; 12 Mar 19=0.1; 15 Jul=0.1; 29 Oct 19=0.1

  2. #2
    BAB, Beware of a Good News Overload --- best to ration it over many days! Super Congrats !

    Djin

  3. #3
    Senior User
    Join Date
    Feb 2017
    Posts
    178
    Djin....and I got an update on the polyploid giant cancer cells and EP53 research. Dr. Pienta said he could get some of the EP53 from a local elephant. Unfortunately, in its current form it would destroy my liver! But, the research is gaining even more momentum. The polyploid's are in EVERY kind of cancer, and they constitute 3% of all cancer cells. Stay tuned....
    2010-PSA 3.59; 2011-PSA 3.58; 2012-PSA 5.28, 4.26; 2013-PSA 5.98, 7.37; 2014-PSA 5.90, 4.70; 2015-PSA 5.18, 7.35
    RALP 16 March 17, Wesley Long, Greensboro, NC
    Pathology: pT3a, pN1 Gleason 4+5=9 adenocarcinoma with + surgical margin at bladder neck; 3 of 16 lymph nodes positive; neg seminal vesicles, vasa deferens
    Referral to Dr. Ken Pienta, Clinical Dir Research, Brady Center, Johns Hopkins
    Enrolled in Clinical Trial IRB002120414 “Phase II Study of definitive therapy for oligometastatic prostate cancer post surgery"
    Completed: Docetaxel 12 Jun 17, 3 Jul 17, 24 Jul 17, 14 Aug 17, 15 Sep 17
    Lupron every 90 days for two years. Completed March 2019
    Bone/Body Scans - 15 Sep 17 - neg; 15 Mar 18 - neg; 14 Sep 18 - neg; 17 Mar 19 - neg
    EBRT: 69 Gy total (46 to fossa, 23 boost to suspect areas) 1st treatment 28 Sep 17, last 22 Nov 17
    PSA: 25 May 17=0.2; 5 Sep 17=0.1; 18 Dec 17=0.1; 6 Mar 18=0.1; 29 May 18=0.1; 5 Sep 18=0.1; 17 Dec 18=0.1; 12 Mar 19=0.1; 15 Jul=0.1; 29 Oct 19=0.1

  4. #4
    Quote Originally Posted by BAB View Post
    Djin....and I got an update on the polyploid giant cancer cells and EP53 research. Dr. Pienta said he could get some of the EP53 from a local elephant. Unfortunately, in its current form it would destroy my liver! But, the research is gaining even more momentum. The polyploid's are in EVERY kind of cancer, and they constitute 3% of all cancer cells. Stay tuned....
    I'm rooting for both you and him! His hypothesis offers a single mechanism that would explain how perhaps all or most cancers "outwit" such diverse treatments as HT, chemo, RT, immunotherapy.... they all constitute environmental stress from the cancer's point of view, and its response is to do something akin to animals growing wings (evolutionarily speaking) or plant seeds having structures to disperse in the wind..... metastasize by his proposed mechanism and travel someplace less stressful.

    Djin

  5. #5
    Bab, why does your JH team not use 2 decimal PSA?
    YOB 1957

    DX 12/18, GS 8, 4+4 6/12 cores, LL Apex 100%, LM Apex 60%, LL Mid 50%, LMM 40%, LL Base 5%, LM <5%, Right side negative.

    3/6/19. Pathology - Grade Group 4 Intraductal Carcinoma
    T3aNO, 1 mm EPE, GS8, 21 mm uni-focal tumor involved 10% of prostate.

    7 Nodes, SV, SM, PNI, and BNI were negative.

    LVI and Cribriform pattern present.

    Decipher .86 High Risk.

    Post Surgery PSA
    3/25/19 .03. (28 days)
    4/25/19 <.03. (58 days)
    5/25/19 <.02. (88 days)
    9/10/2019. <.02. (198 days)

    3 Part Modality Treatment

    2/25/19 Robotic Laparoendoscopic Single Site Surgery outpatient Cleveland Clinic,

    ADT - started 6/19, end date 6/21.

    ART - Completed 9/26/19. (78 Gy, yes, I glow in the dark)

  6. #6
    Senior User
    Join Date
    Feb 2017
    Posts
    178
    The lab report shows the less than symbol and 0.1. There’s an adjectival statement that says this constitutes an undetectable reading. Neither my local folks nor JH have used the ultra sensitive PSA in the 2+ years I’ve been dealing with PCa.

  7. #7
    Congrats BAB! Great News Again!

    Keep The "0" in front of the decimal point!

    MF
    PSA: Oct '09 = 1.91, Oct '11 = 2.79, Dec '11 = 2.98 (PSA, Free = 0.39ng/ml, % PSA Free = 13%)
    Referred to URO MD
    Jan '12: DRE = Positive: "Left induration"
    Jan '12: Biopsy = 6 of 12 Cores were Positive: 1 = G7 (3+4) and 5 = Gleason 6
    Referred to URO Surgeon
    March '12: Robotic RP: Left: PM + EPE. MD waited in surgery for preliminary Path Report then excised substantial left adjacent tissue(s) down to negative margins and placed 2 Ti clips for SR guidance, if needed in future.
    Pathology: Gleason (3+4) pT3a pNO pMX pRO c tertiary pattern 5 / Prostate Size = 32 grams / Tumor = Bilateral: 20% / PNI: present
    3 month Post Op standard PSA = <0.1 ng/ml
    1st uPSA at 7 months Post Op = 0.018 ng/ml
    uPSA remains "stable" at 91 Months Post Op: Mean = 0.022 (22x uPSAs: Range 0.017 - 0.032) LabCorp: Ultrasensitive PSA: Roche ECLIA
    Continence = Very Good (≥ 99%)
    ED = present

  8. #8
    I had all my procedures in Greensboro,Alliance Urology, I can not say enough good things about them.

  9. #9
    Experienced User
    Join Date
    Feb 2019
    Posts
    72
    BAB,

    Fantastic news Brother!

    Take care,

    Josey
    DOB 6/27/69
    12/21/18 1st PSA 25
    1/9/19 PSA 21.7, Free 1.86
    1/17/19 TRUS biopsy:
    PNI+ on left
    MD Anderson review of slides: 12/12 cores positive
    RB 55% 3+4=7
    RM 29% 3+3=6
    RA 12% 3+4=7
    LB 44% 4+3=7
    LM 84% 4+3=7
    LA 100% 3+4=7
    RBL 2% 3+4=7
    RML 24% 3+4=7
    RAL 26% 3+4=7
    LBL 87% 4+3=7
    LML 100% 4+3=7
    LAL 100% 4+3=7
    CT and bone scans negative
    MRI: NVI, SVI, rectum, bladder neck, sphincter, LNs: negative
    EPE negative, however, lesion in left peripheral gland abuts capsule along the left anterior,
    lateral and posterior lateral aspect of the gland.
    4/9/19 Began 6 months Lupron + Zytiga
    PSA 5/7/19 2.3
    PSA 5/24/19 1.3
    PSA 6/27/19 0.4
    PSA 7/15/19 0.3

 

Similar Threads

  1. Zero Club membership maintained
    By jdsky in forum Prostate Cancer Forum
    Replies: 7
    Last Post: 05-18-2019, 10:03 PM
  2. Zero Club Membership Renewed - SRT Question
    By mikesimm in forum Prostate Cancer Forum
    Replies: 7
    Last Post: 03-06-2018, 10:34 PM
  3. Zero Club Membership
    By sawdustmaker in forum Prostate Cancer Forum
    Replies: 14
    Last Post: 03-31-2017, 01:53 AM
  4. Zero club membership renewal
    By wishbonedays in forum Prostate Cancer Forum
    Replies: 11
    Last Post: 01-19-2017, 04:56 AM
  5. Got my membership in The Zero Club!
    By DriscollOFD in forum Prostate Cancer Forum
    Replies: 13
    Last Post: 04-26-2015, 11:03 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •