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Thread: Gleason score 7.2?

  1. #1

    Gleason score 7.2?

    Someone on another forum that has nothing to do with cancer confided to me he had been diagnosed with prostate cancer, he said he had "2 biopsies, the first was Gleason 7.2 and the second was Gleason 7.0" I thought he was confused with PSA scores but he said no his psa had climbed from 5.6 to 8.4.

    I havent heard of a Gleason 7.2. I know a Gleason 7 can be 3+4 or 4+3 (I had one core of gleason 7 3+4 of my own back when I had a Prostate) What is a Gleason 7.2, or is he confused about what the doctor told him?



    On another note, I just had my 9 month checkup from my surgery. I am doing fine, psa is <.13, no incontinence and ED is manageable. Thanks to everyone who answered my questions those months ago, now I want to pay it forward and help other guys.
    Age 54
    no previous PSA data. PSA in Feb 6.1, 2nd PSA April 5.6, biopsy 5/17/18
    2 of 12 cores Gleason 6, left side
    1 core Gleason 7 (3+4), confirmed by Dr Epstiens lab.
    RALP on 11/28/18
    Post surgical pathology Gleason 7 (3+4)

  2. #2
    Senior User
    Join Date
    Nov 2016
    Posts
    302
    Not sure on the 7.2, I know another site refers to 3+4 as 7a and 4+3 as 7b.
    Age at Dx 57
    PCa History: Father, Uncles, Grandfathers

    Oct 2016 Biopsy 12 core: Adenocarcinoma, Gleason 4+3=7 Grade Group 3) w/PNI
    Left Lateral Base: Suspicious
    Left Lateral Mid: PIN
    Left Base: 4+3=7 (60% pattern 4) Core involvement 30% (5mm)
    Right Base: Suspicious
    Right Apex: 3+3=6 Core involvement 60% (7mm) discontinous
    Right Lateral Mid: 3+3=6 Core involvement 10% (1mm)
    Right Lateral Apex: 3+3=6 Core involvement 10% (1mm)

    Jan 2017 DaVinci - Dr. Grant Taylor - Pathology = pT2c or pT3a; Gleason 4+3=7; Weight: 42g

    Jun 2019 AMS800 installed - Dr. David Rapp - Jul 2019 activated

    ED: Light to moderate

    (Note: All PSA tests prior to Jun19 were done by LabCore)
    PSA_TESTS

    Apr 2016=5.1
    Jul 2016=4.7
    Aug 2016=5.13

    ----Surgery----

    Mar17<0.01
    Jul17<0.01
    Oct17<0.01
    Jan18<0.01
    May18<0.01
    Nov18<0.01
    Jan19<0.01
    Jun19<0.02

  3. #3
    Senior User
    Join Date
    Jun 2017
    Posts
    114
    Never heard of a 7.2

    Question for you though, is <.13 a typo?
    PSA 12/12 3.74
    PSA 3/14 3.2 DRE neg
    PSA 9/14 2.68 DRE neg
    PSA 12/15 3.92 DRE neg
    Biopsy 2/16 negative
    PSA 3/17 7.5 DRE neg
    3T MRI 4/17
    PSA 5/17 5.9
    Fusion Biopsy 5/17
    Positive PCa 6/5/17, Diagnosed @ 56
    Left Lateral Base, 4+3
    Left Lateral Mid, 3+3
    MR Lesion 3+4, PI present
    RALP performed 8/30/17
    Gleason re-graded to 3+4, pT2c pN0
    Margin focally involved by one tumor over a length of <.1 cm at left posterior superior margin
    PCa found in right mid as well (surprise to Surgeon & Uro)
    Cath for 2 weeks, dry since removal
    Post op PSA; 3mo <.04, 6mo <.04, 9mo <.04, 12mo <.04, 18mo <.04

  4. #4
    Hi Roadranger. I've no idea what those "Gleason" scores are. We already have Gleason Grades, Gleason Scores, and Gleason Grade Groups. We really don't need any further complications it sounds like someone confused PSA values with Gleason scores.

    May I ask what your pathology grading was after your surgery, pT2 or pT3? Your PSA of <0.13 has piqued my curiosity. Are you sure there is a less-than sign and two digits after the decimal? I ask because 0.13 is a strange lower limit for a PSA test. Usually <0.1 is reported when the PSA is "undetectable" on a standard test. Do you know the name of the lab that did the test? Perhaps you got the result from your doc's portal or a reported value, rather a copy of the actual lab report.

    All the best,

    Djin
    Last edited by DjinTonic; 09-17-2019 at 10:46 PM.
    69 yr at Dx, BPH x 20 yr, 9 (!) neg. Bx, PCA3-
    7-05-13 TURP for BPH (90→30 g) path neg., then 6-mo. checks
    6-06-17 Nodule on R + PSA rise on finasteride: 3.6→4.3
    6-28-17 Bx #10: 2/14 cores: G10 (5+5) 50% RB, G9 (4+5) 3% RLM
    Bone scan, CTs, X-rays: neg.
    8-7-17 Open RP, neg. frozen sections, Duke Regional
    SM EPE BNI LVI SVI LNI(16): negative, PNI+, nerves spared
    pT2c pN0 pMX acinar adenocarcinoma G9 (4+5) 5% of prostate (4.5x5x4 cm, 64 g)
    11-10-17 Decipher 0.37 Low Risk: 5-yr met risk 2.4%, 10-yr PCa-specific mortality 3.3%
    Dry; ED OK with sildenafil
    9-16-17 (5 wk) PSA <0.1
    LabCorp uPSA, Roche ECLIA:
    11-28-17 (3 m ) 0.010
    02-26-18 (6 m ) 0.009
    05-30-18 (9 m ) 0.007
    08-27-18 (1 yr.) 0.018 (?)
    09-26-18 (13 m) 0.013 (30-day check)
    11-26-18 (15 m) 0.012
    02-25-19 (18 m) 0.015
    05-22-19 (21 m) 0.015
    08-28-19 (2 yr. ) 0.016
    Avg. = 0.013

  5. #5
    It was a typo, my psa has bee <.1 since my first post surgery psa test

    I asked him about the 7.2, he said yes that was his gleason score after a biopsy, not a psa score. Iam thinking he got confused by what the doctor told him. I'll bet it is a Gleason 7 as he has surgery scheduled next month. I tried explaing to him about gleason scoring to get some clarification but he didnt reply to that. we have been talking by email only. This isnt someone I know, just someone I talked to on another non cancer forumn
    Age 54
    no previous PSA data. PSA in Feb 6.1, 2nd PSA April 5.6, biopsy 5/17/18
    2 of 12 cores Gleason 6, left side
    1 core Gleason 7 (3+4), confirmed by Dr Epstiens lab.
    RALP on 11/28/18
    Post surgical pathology Gleason 7 (3+4)

  6. #6
    Quote Originally Posted by Roadranger82 View Post
    It was a typo, my psa has bee <.1 since my first post surgery psa test

    I asked him about the 7.2, he said yes that was his gleason score after a biopsy, not a psa score. Iam thinking he got confused by what the doctor told him. I'll bet it is a Gleason 7 as he has surgery scheduled next month. I tried explaing to him about gleason scoring to get some clarification but he didnt reply to that. we have been talking by email only. This isnt someone I know, just someone I talked to on another non cancer forumn
    I agree. As we, know, the G score is a sum of the most prevalent and second-most prevalent G grades. Those grades are, of course, whole numbers from 3 to 5, so decimals don't enter the pictures.

    I personally like the convention of always writing decimal numbers less than zero with a leading 0 before the decimal point: <0.1
    This is how decimals are written in lab reports and journal papers without exception.

    The zero also serves as a check that the decimal is where it's meant to be, e.g. that .15 isn't a typo for 1.5

    Djin
    Last edited by DjinTonic; 09-19-2019 at 01:20 PM.

 

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