A website to provide support for people who have or have had any type of cancer, for their caregivers and for their family members.
Results 1 to 1 of 1

Thread: Possible expanded use of PARP inhibitors in cancer

  1. #1

    Possible expanded use of PARP inhibitors in cancer

    https://www.biospace.com/article/res...n-lung-cancer/

    Inducing PARP expression via a drug, then treating cancer with a PARP inhibitor. Early study.
    A new study shows that a PARP inhibitor combined with a DNA methyltransferase (DNMT) inhibitor may be a new way of treating some lung cancers.

    A 2nd article on PARP expansion:
    https://www.sciencedaily.com/release...0724110938.htm
    The PARP inhibitors also attack the machinery that makes proteins, called ribosomes.

    "Cancer cells are addicted to ribosomes. Cancer cells grow fast and must make proteins to support cell division and other essential processes going on in the cell. If you can slow down or inhibit the production of ribosomes, then you can slow down the growth of the cancer cell," Dr. Kraus said.
    Last edited by lancepeace; 10-19-2019 at 07:42 PM.

 

Similar Threads

  1. Car T cell coverage is expanded
    By fighterm in forum Lymphoma - Hodgkin's and Non-Hodgkin's Lymphoma Forum
    Replies: 1
    Last Post: 08-20-2019, 12:11 PM
  2. Replies: 0
    Last Post: 04-13-2018, 02:38 PM
  3. PARP Inhibitors for Uterine Cancers
    By gdpawel in forum Uterine and Endometrial Cancer Forum
    Replies: 1
    Last Post: 04-29-2011, 05:13 PM
  4. PARP Inhibitors for Melanoma?
    By gdpawel in forum Melanoma and Skin Cancer Forum
    Replies: 1
    Last Post: 04-29-2011, 05:10 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •