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Thread: CA 19-9 and CEA

  1. #1

    CA 19-9 and CEA

    Hi, All.
    Today I had my CA 19-9 checked. Last spring it had clmbed to over 10,000, and then after doing IMRT it fell to the 400s in August and September. This month it was back up in the 700s. However, the CEA, which had been almost consistently over 5, even reaching over 8, was a little above 3. The doctor almost never mentions the CEA, but today he did, saying that it was hopeful to see that it had dropped. He said that with rising CA 19-9 there can be a couple of other factors besides tumor activity causing the increase. He said the movement of the CEA reflects tumor activity, and there aren't really other possibilities that make it increase or decrease (though the other doctor said smoking can cause a rise, but I don't smoke).
    So, I'm left wondering, was today's news good news or bad news?
    Last edited by jackieb501; 10-22-2019 at 04:16 AM.
    February 2016- diagnosed with PC
    March 2016- inoperable due to arteries, also liver mets suspected
    March 2016-January 2017 -Gemzar/Abraxane
    February 2017 surgery-PC tumour and liver mets removed at same time
    July 2018 Back on Gemzar/Abraxane due to rising CA 19-9. Scans were clear.
    January 2019 Tried FOLFIRINOX after G/A became ineffective. FFX doesn't work. CA 19-9 rising
    February 2019 two small tumors appear on liver
    May 2019 - CA 19-9 skyrocketing. Started IMRT radiation treatment.
    August 2019 MRI done. No Evidence of Disease (NED). CA 19-9 dropped significantly. Still not normal range.

  2. #2
    Senior User
    Join Date
    Mar 2018
    Posts
    159
    BUMP

    anybody. I also had my first CEA but had no baseline to compare it with. Mine was an 8. My doc told me it was another GI marker.....but not as useful as CA19-9. Since neither are specifically for Pancreas, they go with whichever they think is giving them the better read Would love to see if anyone has more info.
    Thanks
    +++++++++++++++++++++++++++++
    53 yrs old
    3/8/18 went to ER w/what i thought to be gall bladder issues...CT and MRI found 1.5 cm spot on body/neck of pancreas
    Followed up with EUS No mets/contained
    3/18 started 4 cycles of Gem/Abrax
    5/18 CT scan showed tumor shrinkage .97cm
    7/18 Pre surgery CT scan shows slight tumor growth (1.2cm) could be necrosis.
    8/3/18 distal pancreatomy/splenectomy-open procedure. No mets, 1 lymph node involvement.(local) Staged 2B
    9/18 CA19 33 NORMAL
    10/10/18 Starting 3 mos Folfirinox adjuvant therapy.
    5/19 CT scan shows enlarged lymph node at surgical site. EUS biopsy determines cancer. Local and contained.
    6/19 Begin radiation. View Ray MRI 5 day regimen.
    8/19 CA19-9 down! no signs of lymph node!!!
    10/2 3 weeks of abdominal/right side pain. CT scan shows small (1mm) soft tissue nodule suspect for Peritoneal Mestastasis. CA 19- way up (1010)

  3. #3
    Thank you Susan! It's so nice to get a reply on a support forum!
    February 2016- diagnosed with PC
    March 2016- inoperable due to arteries, also liver mets suspected
    March 2016-January 2017 -Gemzar/Abraxane
    February 2017 surgery-PC tumour and liver mets removed at same time
    July 2018 Back on Gemzar/Abraxane due to rising CA 19-9. Scans were clear.
    January 2019 Tried FOLFIRINOX after G/A became ineffective. FFX doesn't work. CA 19-9 rising
    February 2019 two small tumors appear on liver
    May 2019 - CA 19-9 skyrocketing. Started IMRT radiation treatment.
    August 2019 MRI done. No Evidence of Disease (NED). CA 19-9 dropped significantly. Still not normal range.

  4. #4
    Senior User
    Join Date
    Mar 2018
    Posts
    159
    you got it lady!
    +++++++++++++++++++++++++++++
    53 yrs old
    3/8/18 went to ER w/what i thought to be gall bladder issues...CT and MRI found 1.5 cm spot on body/neck of pancreas
    Followed up with EUS No mets/contained
    3/18 started 4 cycles of Gem/Abrax
    5/18 CT scan showed tumor shrinkage .97cm
    7/18 Pre surgery CT scan shows slight tumor growth (1.2cm) could be necrosis.
    8/3/18 distal pancreatomy/splenectomy-open procedure. No mets, 1 lymph node involvement.(local) Staged 2B
    9/18 CA19 33 NORMAL
    10/10/18 Starting 3 mos Folfirinox adjuvant therapy.
    5/19 CT scan shows enlarged lymph node at surgical site. EUS biopsy determines cancer. Local and contained.
    6/19 Begin radiation. View Ray MRI 5 day regimen.
    8/19 CA19-9 down! no signs of lymph node!!!
    10/2 3 weeks of abdominal/right side pain. CT scan shows small (1mm) soft tissue nodule suspect for Peritoneal Mestastasis. CA 19- way up (1010)

  5. #5
    Regular User
    Join Date
    Oct 2019
    Posts
    13
    Hi,

    In my case, my mother was not secreting significant amount of CA 19-9. (Though she is not confirmed as Lewis antigen negative.) Upon diagnosis, her CEA level was borderline elevated, and her CA 125 was slightly elevated (low 30s). After the first Folfirinox, those numbers dropped to normal.

 

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