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Thread: 18-month Post HDR BT PSA results

  1. #1

    18-month Post HDR BT PSA results

    Yesterday I got two great numbers. Shot my lowest golf score of 77 and more importantly, my 18-month post-HDR BT PSA is 0.4!!! The initial was 5.7. 1.0 at 12 months. I am so grateful!
    65 YO healthy man
    PSA had been 4.1/2 for a couple of years,
    PSA 5/1/17 4.6,
    Multiparametric MRI, 5/15/17 showed a lesion
    13 core needle biopsy 3 cores positive 3+3 and one positive in the lesion, may be overlap
    All cores less than 30%
    8/22/17 - second opinion pathology shows a small amount of (3+4) in one core, < 5%, ordered decipher to inform next steps
    9/27/17 -Decipher test shows intermediate-risk so now exploring treatment options.
    2/6/18 - completed HDR-BT
    5/3/18 Post HDR BT PSA 1.3
    9/18/18 PSA 1.2
    4/1/19 PSA 1.0 Testosterone 475
    10/28/19 PSA 0.4 Testosterone 524
    Thanks, Denis
    "One day at a time"

  2. #2
    +

    Djin

  3. #3
    Experienced User
    Join Date
    Oct 2019
    Posts
    88
    Congratulations! Wonderful news!
    Wife posting
    Age 51
    PSA 9/2019 - 4.8
    fPSA - 9%
    4K score 12%
    Bx 9/2019
    Final Diagnosis - prostate carcinoma
    Highest Gleason Score - 3+3=6
    Number of cores positive - 4
    Percent of cores positive - 28.6% (4 of 14 cores - 12 samples taken. 2 broke in half)
    Maximum % of tumor in positive cores - 60%
    Overall prostatic tissue involvement - 5.8%
    Perineural invasion - present
    Lymph-vascular invasion - not identified
    Periprostatic fat invasion/extrsprostatic extension - not identified

    Left base - G3+3=6. 4% involved. Perineural invasion present.
    Right apex - G3+3=6. 40% involved.
    Right lateral mid - G3+3=6. 5% involved.
    Left lateral apex - G3+3=6. 40% involved.

    OncoDX score 23. Low Risk.
    High Grade Disease 14%
    Non Organ Confined Disease 16%

  4. #4
    Congrats! Looks like your "PSA Deep Dive" is approaching the ocean floor! You are The Forum's official HDR BT Expert!

    My neighbor underwent HDR BT and is on a similar PSA trajectory and has had 0 complaints or unwanted issues!

    Will be looking for your debut on The PGA Tour Champions!


    MF
    Last edited by Michael F; 10-29-2019 at 01:42 PM.
    PSA: Oct '09 = 1.91, Oct '11 = 2.79, Dec '11 = 2.98 (PSA, Free = 0.39ng/ml, % PSA Free = 13%)
    Referred to URO MD
    Jan '12: DRE = Positive: "Left induration"
    Jan '12: Biopsy = 6 of 12 Cores were Positive: 1 = G7 (3+4) and 5 = Gleason 6
    Referred to URO Surgeon
    March '12: Robotic RP: Left: PM + EPE. MD waited in surgery for preliminary Path Report then excised substantial left adjacent tissue(s) down to negative margins and placed 2 Ti clips for SR guidance, if needed in future.
    Pathology: Gleason (3+4) pT3a pNO pMX pRO c tertiary pattern 5 / Prostate Size = 32 grams / Tumor = Bilateral: 20% / PNI: present
    3 month Post Op standard PSA = <0.1 ng/ml
    1st uPSA at 7 months Post Op = 0.018 ng/ml
    uPSA remains "stable" at 91 Months Post Op: Mean = 0.022 (22x uPSAs: Range 0.017 - 0.032) LabCorp: Ultrasensitive PSA: Roche ECLIA
    Continence = Very Good (≥ 99%)
    ED = present

  5. #5
    Top User garyi's Avatar
    Join Date
    Apr 2017
    Posts
    1,473
    Wonderful results, Denis!
    72...LUTS for the past 7 years
    TURP 2/16,
    G3+4 discovered
    3T MRI 5/16
    MRI fusion guided biopsy 6/16
    14 cores; four G 3+3, one G3+4,
    CIPRO antibiotic = C. Diff infection 7/16
    Cured with Vanco for 14 days
    Second 3T MRI 1/17
    Worsened bulging of posterior capsule
    Oncotype DX GPS 3/17, LFP risk 63%, Likelihood of Low
    Grade Disease 81%, Likelihood of Organ Confined 80%
    RALP 7/13/17 Dr. Gonzaglo @ Univ of Miami
    G3+4 Confirmed, Organ confined
    pT2 pNO pMn/a Grade Group 2
    PSA 0.32 to .54 over 3 months
    DCFPyl PET & ercMRI Scans - 11/17
    A one inch tumor still in prostate bed = failed surgery
    All met scans clear
    SRT, 2ADT, IMGT 70.2 Gys @1.8 per, completed 5/18
    Radiation Procitis, and Ulcerative Colitis flaired after 20 years
    PSA <.006 9/18, .054 11/18, .070 12/18, .067 2/19, .078 5/19, .074 7/19, .081 9/19, .116 11/19
    We'll see....what is not known dwarfs what is thought to be fact

  6. #6
    Thanks All!
    65 YO healthy man
    PSA had been 4.1/2 for a couple of years,
    PSA 5/1/17 4.6,
    Multiparametric MRI, 5/15/17 showed a lesion
    13 core needle biopsy 3 cores positive 3+3 and one positive in the lesion, may be overlap
    All cores less than 30%
    8/22/17 - second opinion pathology shows a small amount of (3+4) in one core, < 5%, ordered decipher to inform next steps
    9/27/17 -Decipher test shows intermediate-risk so now exploring treatment options.
    2/6/18 - completed HDR-BT
    5/3/18 Post HDR BT PSA 1.3
    9/18/18 PSA 1.2
    4/1/19 PSA 1.0 Testosterone 475
    10/28/19 PSA 0.4 Testosterone 524
    Thanks, Denis
    "One day at a time"

 

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