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Thread: Infection after first treatment

  1. #1
    Newbie New User
    Join Date
    Nov 2019

    Infection after first treatment

    Hello! My dad was recently diagnosed with pancreatic cancer. His tumor is in the head of the pancreas and it is considered borderline resectable. He just started his first treatment of folfirinox 2 weeks ago. He should have started his second round today, however he caught a nasty bacterial infection and has to have antibiotics administered 3 times daily for 4 weeks. This means he can not receive his next treatment until the infection clears and antibiotics are finished. Iím worried that the tumor will spread over the next 4 weeks before his next treatment. Has anyone had this happen? Is this reason to be concerned? Thank you so much!

  2. #2
    Senior User
    Join Date
    Mar 2018
    I'm sorry that had to happen right when he's getting started - bummer. The first time I missed a treatment because of inadequate platelet count I was very depressed and worried that I was slipping at losing the fight. After a year and a half and missing many I have gotten used to the somewhat erratic rhythm that Chemo can have. I believe there is even some studied evidence that missing treatments here and there has no overall effect on survival time. I hope he heals quickly.
    Mar. '18 - Diagnosed Stage IV with liver mets CA-19 124,000
    Apr. '18 - Started chemo - Gem, Abrx, Cis
    July and Sept '18 - Ct scan - all tumors shrinking
    Oct. '18 - CA-19 - 1,495
    Oct. '18 - Started Gem, Abrx 1/2 dose
    - Ca-19 up to over 6,000
    April '19 - Started 5-fu, Abraxane, Oxaliplatin
    Ca-19 down to 600, missing many doses due to
    low platelets
    Aug '19 - Started Irrinotecan, abraxane, cysplatin
    missing doses, low platelets
    Sept '19 - Ca-19 holding steady, ct scan shows 2 small
    lung nodules - 3mm, 5mm, blood clot in pulmonary
    vein, primary and liver mets stable started blood thinner
    Oct. '19 Switched back to POLF treatment - Paclitaxel,Oxaliplatin,
    Leucovorin, 5FU

  3. #3
    It seems like it wouldn't spread that quickly.
    February 2016- diagnosed with PC
    March 2016- inoperable due to arteries, also liver mets suspected
    March 2016-January 2017 -Gemzar/Abraxane
    February 2017 surgery-PC tumour and liver mets removed at same time
    July 2018 Back on Gemzar/Abraxane due to rising CA 19-9. Scans were clear.
    January 2019 Tried FOLFIRINOX after G/A became ineffective. FFX doesn't work. CA 19-9 rising
    February 2019 two small tumors appear on liver
    May 2019 - CA 19-9 skyrocketing. Started IMRT radiation treatment.
    August 2019 MRI done. No Evidence of Disease (NED). CA 19-9 dropped significantly. Still not normal range.

  4. #4
    Newbie New User
    Join Date
    Nov 2019
    Thank you for the responses! I guess Iím just nervous/scared because his last scans showed no spread but the tumor was up almost against an artery so with chemo the hope is to shrink the tumor then have surgery. I just donít want this set back to cause his situation to drastically change because of missing chemo.


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